Publications by authors named "Shunsuke Matsuno"
Pericardial effusion (PE) presentation varies from an incidental finding to a life-threatening situation; thus, its etiology and clinical course remain unknown. The aim of the present study was to retrospectively investigate these factors.We analyzed 171 patients (0.
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- A study examined the effectiveness of convolutional neural networks (CNNs) integrated with electrocardiograms (ECGs) for identifying hypertrophic cardiomyopathy (HCM) and dilated HCM (dHCM) in a large patient dataset (19,170 total, with 140 HCM/dHCM cases).
- The analysis focused on two diagnostic models—one for overall disease detection and another that considered different disease subtypes—showing that while overall sensitivity started at 76%, it reached 100% when specific conditions were met (diagnostic probability ≥ 0.9 and left ventricular hypertrophy present).
- The research concluded that while initial detection rates of HCM or dHCM using CNNs in
Article Synopsis
- * The CNN model achieved a high area under the curve (AUC) score of 0.936 for AD detection with eight-lead ECGs but had a low overall positive predictive rate (PPR) of 7%. However, the PPR improved significantly to 35% for patients with high D-dimer levels and a history of hypertension.
- * The single-lead V1 ECG also demonstrated strong performance, with an A
Article Synopsis
- - We created a convolutional neural network (CNN) to detect atrial fibrillation (AF) using sinus rhythm ECGs (SR-ECG), analyzing data from 616 AF cases and 3,412 sinus rhythm cases among over 19,000 patients.
- - The CNN model showed strong performance with an area under the curve (AUC) of 0.872 for detecting AF with eight-lead ECGs, indicating high accuracy in distinguishing AF from sinus rhythm.
- - Notably, the double-lead ECG using leads I and V1 had a similar AUC of 0.871, suggesting that this simpler approach could be a viable alternative for AF screening in clinical settings.
Article Synopsis
- - Advances in PCI devices have increased the number of patients eligible for complex revascularization procedures, including those with serious health issues or complicated heart conditions (CHIP).
- - This review compares two specific cases of CHIP interventions conducted in the USA, illustrating differences in practice between American and Japanese operators.
- - Key discussion points include patient selection, collaborative decision-making through heart teams, hemodynamic support usage, and the potential for learning and improving outcomes from international practices.
Article Synopsis
- The study aimed to create an AI model for detecting the dilated phase of hypertrophic cardiomyopathy (dHCM) using digital electrocardiograms (ECGs).
- It utilized a retrospective analysis of 17,378 ECGs from a database, identifying 54 dHCM patients and evaluating the model's effectiveness with different lead configurations (eight-lead, single-lead, and double-lead).
- The results showed high accuracy, with the single-lead V5 ECG performing almost as well as the eight-lead ECG, suggesting it as a viable option for dHCM screening.
Purpose Of The Review: The goal of this paper is to review the current evidence surrounding CTO PCI in patients with low EF, the most high-risk population to treat. We also present pertinent case examples and offer practical tips to increase success and lower complications when performing CTO PCI in patients with low EF.
Recent Findings: In a prospective randomized control study, greater improvement in angina frequency and quality of life, assessed by the Seattle Angina Questionnaire, was achieved by CTO PCI compared to optimal medical therapy.
High alkaline phosphatase (ALP) levels are reported to be associated with an increased risk of cardiovascular events in patients with chronic kidney disease (CKD). Given the pathological link with CKD, a similar relationship may exist in patients with atrial fibrillation (AF). We retrospectively evaluated 1,719 patients with AF and normal hepatic function who were registered in the Shinken Database between November 2011 and March 2017.
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- A study was conducted to investigate the relationship between operator experience and technical success rates in percutaneous coronary intervention for chronic total occlusion (CTO-PCI) using data from two major Japanese registries.
- The analysis showed that the overall success rate and in-hospital major adverse events were similar for both highly experienced and less experienced operators, indicating that less experienced operators can achieve good outcomes.
- However, more experienced operators had a significantly higher success rate when using the primary antegrade approach, while there was no notable difference in success with the primary retrograde approach.
Glasgow prognostic score (GPS) has been used to evaluate inflammatory response and nutritional status. This study aimed to investigate the impact of nutritional status on cardiac prognosis by using GPS in patients after undergoing percutaneous coronary intervention (PCI). We included 862 patients who underwent PCI for stable angina pectoris between 2015 and 2018.
View Article and Find Full Text PDFBackground: Older adults with atrial fibrillation (AF) have highly diverse risk levels for mortality, heart failure (HF), thromboembolism (TE), and major bleeding (MB), thus an integrated risk-pattern algorithm is warranted.
Methods: We analyzed 573 AF patients aged ≥ 75 years from our single-center cohort (Shinken Database 2010-2018). The 3-year risk scores (risk probability) for mortality (M-score), HF (HF-score), TE (TE-score), and MB (MB-score) were estimated for each patient by logistic regression analysis.
Article Synopsis
- The study aimed to investigate the relationship between the number of medications (polypharmacy) and outcomes in older adults (>75 years) with cardiovascular diseases.
- Data from 2,089 patients were analyzed, divided into three groups based on medication count: fewer than 3, 3-7, and 8 or more medications.
- Results indicated a higher incidence of all-cause death in those taking 8 or more medications, but some heart disease subgroups did not show the same risk, suggesting that more medications might sometimes be beneficial rather than harmful in cardiovascular treatment.
Aim: Polypharmacy is known to be a risk factor for falls or bone fracture (F/F) in elderly patients. However, this relationship is not fully described in patients with non-valvular atrial fibrillation (NVAF), for which F/F may lead to serious clinical outcomes, including major bleeding.
Methods: We analyzed 509 elderly (aged ≥75 years) patients with NVAF who had recently visited a hospital specializing in cardiology, of which 272 patients had paroxysmal atrial fibrillation (PAF) and 237 had persistent/permanent atrial fibrillation (PeAF).
The incidence of ischemic stroke (IS) increases in patients with enlarged left atrium (LA) irrespective of whether or not the existence of atrial fibrillation (AF). In such situation, it is unclear whether the impact of LA on incidence of IS still significant in young, non-AF patients with enlarged LA who are primarily unconcerned on anticoagulation therapy. The study population consisted of 18,511 consecutive patients not receiving oral anticoagulants and undergoing echocardiography with measurement of LAD at baseline.
View Article and Find Full Text PDFBackground: Resting 12-lead electrocardiography is widely used for the detection of cardiac diseases. Electrocardiogram readings have been reported to be affected by aging and, therefore, can predict patient mortality.
Methods: A total of 12,837 patients without structural heart disease who underwent electrocardiography at baseline were identified in the Shinken Database among those registered between 2010 and 2017 (n = 19,170).
Background: It has been reported that a large decline in estimated glomerular filtration rate (eGFR) over time is associated with increased incidence of cardiovascular disease. We investigated whether this association differs according to the baseline eGFR.
Methods: A total of 4666 patients (male 71%) with measurements of eGFR at both baseline and 1 year and that had no cardiovascular events at 1-year follow-up were retrieved from the Shinken Database between June 2004 and March 2015.
Background: Diagnosis of atrial fibrillation (AF) based on electrocardiogram (ECG) with sinus rhythm remains a major challenge. Obtaining a panoramic view with hundreds of automatically measured ECG parameters at sinus rhythm on the predictive capability for AF would be informative.
Methods: We used a single-center database of a specialist cardiovascular hospital (Shinken Database 2010-2017; n = 19,170).
Safety of Percutaneous Coronary Intervention for Chronic Total Occlusion in Patients With Multi-Vesel Disease: Sub-Analysis of the Japanese Retrograde Summit Registry.
Cardiovasc Revasc Med
April 2021
Background: The success rate of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) has gradually increased thanks to the continuous development of devices and techniques. However, the impact of multi-vessel disease (MVD) on its success rate and safety is not well known.
Methods: The clinical records of 5009 patients enrolled in the Japanese Retrograde Summit Registry and who had undergone PCI for CTO at 65 centers between 2012 and 2015 were reviewed.
We developed a prediction model of long-term risk after percutaneous coronary intervention (PCI) for coronary chronic total occlusion (CTO) based on pre-procedural clinical information. A total of 4,139 eligible patients, who underwent CTO-PCI at 52 Japanese centers were included. Specifically, 1,909 patients with 1-year data were randomly divided into the derivation (n = 1,273) and validation (n = 636) groups.
View Article and Find Full Text PDFBackground: Ischemic stroke (IS) and major bleeding, which are serious adverse events in patients with atrial fibrillation (AF), could have seasonal variations, but there are few reports.
Methods and results: In the Shinken Database 2004-2016 (n=22,018), 3,581 AF patients (average age, 63.5 years; 2,656 men, 74.
Although bisoprolol is used widely to treat patients with heart failure (HF), little information is available regarding the association between the dose of bisoprolol administered and the bisoprolol plasma concentration (Bis-PC) in real-world clinical practice.This was a single-center, observational study in 114 patients with HF receiving once-daily bisoprolol. After determination of trough Bis-PC, the relationship between the dose of bisoprolol and Bis-PC was analyzed.
View Article and Find Full Text PDFBackground: Percutaneous coronary intervention (PCI) is widely used in patients with chronic total occlusion (CTO), but its benefit in improving long-term outcomes is controversial. We aimed to develop a prediction score for grading "survival advantage" conferred by successful results of CTO-PCI and a scoring system for prediction of the influence of CTO-PCI results on major adverse cardiac and cerebrovascular events (MACCEs).
Methods: Follow-up data of 2625 patients who underwent CTO-PCI at 65 Japanese centers were analyzed.