Publications by authors named "Shunsuke Honma"
Background: No accurate prognostic tool is available for patients with cancer who spend their final days at home. In this study, we examined whether performance status (PS) and the palliative prognostic index (PPI), a well-known prognostic tool in palliative care units, could be used to predict prognosis in the home care setting at the time of intervention by home physicians.
Subjects And Methods: Using medical records, we conducted a retrospective analysis of 132 patients who were referred to the Home Clinic Naginoki for home care for terminal stages of carcinoma in situ.
Article Synopsis
- * A case study of a 75-year-old woman diagnosed with EBV-HLH showed symptoms such as fever, low platelet count, and loss of consciousness, confirmed by hemophagocytosis in bone marrow and EBV DNA in cerebrospinal fluid.
- * Despite treatment following the HLH-2004 protocol and initial improvement in disease markers, the woman ultimately succumbed to multiple organ failure and loss of consciousness, highlighting the rarity and severity of HLH in older
Article Synopsis
- The MEAM regimen, used before auto-PBSCT for malignant lymphoma, was adjusted to include a higher dose of Ara-C to improve drug delivery to the central nervous system.
- A retrospective analysis of 37 cases showed that all patients experienced engraftment with no treatment-related deaths, achieving a 3-year overall survival rate of 80.6% and a progression-free survival rate of 65.7%.
- While the high-dose Ara-C MEAM therapy proved safe and effective, its impact on central nervous system lesions could not be thoroughly assessed due to the limited number of cases.