Publications by authors named "Shunping Lou"
Efficacy and safety of different doses of mifepristone in the treatment of uterine fibroids: A meta-analysis.
Eur J Obstet Gynecol Reprod Biol
December 2024
Article Synopsis
- The study aimed to assess the safety and effectiveness of various doses of mifepristone (2.5 mg to 50 mg) in treating uterine fibroids through a systematic review of randomized controlled trials (RCTs).
- A meta-analysis of 18 studies involving 2,066 patients indicated that mifepristone significantly reduced uterine and fibroid volumes and improved symptoms like pelvic pain and urinary issues compared to a control group.
- While mifepristone showed benefits, it also caused some side effects such as increased endometrial thickness and hot flashes, with the 5 mg/day dose for three months being identified as the potentially best regimen for treatment.