Publications by authors named "Shunpeng Song"
Genome-wide association studies (GWASs) have reproducibly associated ∼40 susceptibility loci with psoriasis. However, the missing heritability is evident and the contributions of coding variants have not yet been systematically evaluated. Here, we present a large-scale whole-exome array analysis for psoriasis consisting of 42,760 individuals.
View Article and Find Full Text PDFBackground/aims: Psoriasis is characterized by lower stratum corneum (SC) hydration and dermal inflammation. Both SC hydration and cutaneous inflammation influence cutaneous resonance running time (CRRT). However, the characteristics of CRRT in psoriatic lesions are largely unknown.
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- Atopic dermatitis is a long-lasting inflammatory skin condition influenced by both genetics and the environment.
- A study involved a genome-wide analysis of atopic dermatitis in a large Chinese Han population and included additional samples from Germany, leading to the identification of new genetic markers associated with the condition.
- The findings reveal new potential genetic factors that contribute to atopic dermatitis and suggest new biological pathways that could be explored for better understanding and treatment.
Background/objectives: Previous studies have demonstrated that sun-induced alteration of epidermal permeability barrier function varies with gender and age. In the present study, we assess the stratum corneum (SC) hydration in sun-exposed males and females.
Methods: A total of 168 subjects (84 males and 84 females) aged 19-75 years were enrolled.
Background/objectives: One phenomenon of skin aging is loss of cutaneous elasticity. Measurement of cutaneous resonance running time (CRRT) is a method to assess skin elasticity. Yet, information regarding the directional changes of CRRT associated with age, body sites and gender is not yet available.
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