Publications by authors named "Shunli Che"
Effects of nanopolystyrene and/or phoxim exposure on digestive function of Eriocheir sinensis.
Comp Biochem Physiol C Toxicol Pharmacol
December 2024
Nanopolystyrene (NP) and phoxim (PHO) are pervasive environmental contaminants that pose a significant threat to the health of aquatic organisms, prompting widespread concern among researchers and the public alike. The hepatopancreas play important roles in the Chinese mitten crab (Eriocheir sinensis), such as digestion, absorption and detoxification. This study assessed the hepatopancreatic toxicity caused by the exposure of Eriocheir sinensis to environmentally relevant concentrations of NP and/or PHO.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the negative impacts of nanopolystyrene (NP) and phoxim (PHO), a common pesticide, on the intestines and gut microbiota of adult crabs over 21 days, highlighting serious histopathological changes, including vacuolar degeneration in epithelial cells.
- Exposure to NP and/or PHO significantly disrupted the balance of intestinal microbiota, increasing harmful bacteria while decreasing helpful ones, particularly noting the rise of pathogens like Spiroplasma and Arcobacter.
- Metabolomic analysis indicated changes in key metabolic pathways, with NP and PHO exposure affecting processes like arachidonic acid metabolism and downregulating neuroactive interactions, suggesting that these substances
Article Synopsis
- Significant concerns have been raised regarding the environmental pollutants phoxim (PHO) and nanopolystyrene (NP) and their effects on the hepatopancreas of Eriocheir sinensis (a type of crab) when exposed to realistic concentrations.
- Subchronic exposure to NP and/or PHO for 21 days caused histological damage, reduced the number of healthy cells, and impaired protective barriers in the hepatopancreas, indicating a toxic effect on this organ.
- The study also found that both individual and combined exposures led to inflammation and disrupted the expression of genes related to oxidative stress, mucus production, and immune response, confirming that NP and PHO pose significant risks to crustacean health.
Nanopolystyrene (NP) and phoxim (PHO) are common environmental pollutants in aquatic systems. We evaluated the toxic effects of exposure to ambient concentrations of NP and/or PHO in the intestines of the Chinese mitten crab (Eriocheir sinensis). Our study showed that histopathological changes were observed in the intestines.
View Article and Find Full Text PDFNanopolystyrene (NP) and cadmium (Cd) are ubiquitous contaminants in aquatic systems. The present study aimed to investigate the toxic effects of exposure to ambient concentrations of NP and/or Cd on the intestinal tract of the Chinese mitten crab (Eriocheir sinensis). Exposure to NP and/or Cd induced oxidative stress, as evidenced by a significant increase in lipid peroxide content (LPO), total antioxidant capacity (T-AOC), and peroxidase activity (POD), and significant decreases in superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) activities in E.
View Article and Find Full Text PDFSesquiterpenoid methyl farnesoate (MF), a crustacean equivalent of insect juvenile hormone (JH III), has essential functions in regulating physiological processes in crustaceans, including reproduction and vitellogenesis. Farnesoic acid O-methyltransferase (FAMeT) is a key rate-limiting enzyme catalyzing the conversion of farnesoic acid (FA) to JH/MF in insects and crustaceans. In this study, a full-length cDNA of EsFAMeT from Eriocheir sinensis was isolated and characterized.
View Article and Find Full Text PDFRNAi silencing of the 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) gene inhibits vitellogenesis in Chinese mitten crab Eriocheir sinensis.
Comp Biochem Physiol A Mol Integr Physiol
January 2022
The sesquiterpenoid methyl farnesoate (MF), a de-epoxide form of insect juvenile hormone III (JH III), plays an essential role in regulating many crucial physiological processes in crustaceans including vitellogenesis and reproduction. 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) is an important rate-limiting enzyme in the mevalonate pathway, which is critical for the synthesis of JH III and MF. In the present study, a full-length cDNA encoding HMGR (EsHMGR) in Eriocheir sinensis was isolated and characterised.
View Article and Find Full Text PDF