Publications by authors named "Shunkang Jin"
Article Synopsis
- - The study investigates the role of intratumoral microbes in colorectal cancer (CRC) but faces technical challenges due to contamination from fecal microbes; hence, it aimed to develop a new method for isolating tumor cell-associated microbiota.
- - Researchers used a combination of immunohistochemistry and 5R-16s rRNA gene sequencing on samples from CRC patients to analyze the distribution and functions of microbiota in tumor tissues, adjacent normal tissues, and different cell types.
- - Results showed that the distribution of bacteria varied significantly based on the sampling site and washing methods, with certain bacterial phyla (Firmicutes and Bacteroidetes) more abundant in conventional samples, while Proteobacteria dominated in cell samples obtained
Chronic stress promotes gastric cancer progression via the adrenoceptor beta 2/PlexinA1 pathway.
Cell Stress Chaperones
February 2024
Article Synopsis
- * Analysis of various datasets revealed that higher levels of PlexinA1 correlate with worse survival in GC patients, and those experiencing chronic stress show elevated expression of certain proteins associated with cancer progression.
- * Experimental studies in mice demonstrated that chronic stress significantly increases tumor size and alters protein expression patterns, suggesting that targeting the epinephrine-β2 adrenergic receptor/PlexinA1 pathway may help mitigate stress-related cancer progression.