Radiological features and therapeutic responses of pulmonary nontuberculous mycobacterial disease in rheumatoid arthritis patients receiving biological agents: a retrospective multicenter study in Japan.

Objective: This study was performed to evaluate the radiological features of and therapeutic responses to pulmonary disease caused by nontuberculous mycobacteria (NTM) in the setting of biological therapy for rheumatoid arthritis (RA).

Methods: We conducted a retrospective chart review of 13 patients from multiple centers who had developed pulmonary NTM disease during biological therapy for RA, including infliximab, etanercept, adalimumab, and tocilizumab.

Results: Most cases were asymptomatic or resulted in only common-cold-like symptoms.

[Usefulness of ursodeoxycholic acid in a case of hepatic sarciodosis].

A 38-year-old man was admitted to our hospital with a diagnosis of pulmonary sarcoidosis accompanied with elevated biliary enzyme levels. Various imaging modalities, and percutaneous liver biopsy confirmed the diagnosis of hepatic sarcoidosis. Abnormalities of biliary enzymes improved after the administration of ursodeoxycholic acid (UDCA).