Reductions in Depression and Anxiety Among Autistic Adults Participating in an Intervention to Promote Healthy Relationships.

Importance: Some autistic adults experience depression and anxiety related to their social relationships. There is a need for evidence-based occupational therapy interventions that decrease depression and anxiety and improve the health of social relationships for autistic adults.

Objective: To determine the feasibility and preliminary effectiveness of the Healthy Relationships on the Autism Spectrum (HEARTS) intervention, a six-session, group-based psychoeducational intervention for the improvement of relationship health.

Scalable Preparation of Sub-Millimeter Double-Shelled AlO Hollow Spheres and Their Rapid Separation from Wastewater after Adsorption of Congo Red.

Porous double-shelled ceramic hollow spheres (PDSs) have attracted extensive attention due to their high specific surface areas and multifunctional designs. When used in wastewater treatment, millimeter or sub-millimeter spheres can be quickly separated from water by commercial sieves. However, the simple, scalable, and low-cost preparation of sub-millimeter PDSs in the solid phase remains a challenge.

Has China's New Round of Collective Forest Reforms Reduced Forest Fragmentation? A Case Study of the Beijing-Tianjin-Hebei Region.

The new wave of reform of collective forestland tenure (NRCFT) in China is considered an important policy for achieving sustainable management of forest resources. The purpose of this study is to investigate the influence of NRCFT on forest fragmentation in the Beijing-Tianjin-Hebei region of China based on a fixed-effects model. The forest fragmentation was analyzed based on the remote sensing images of Landsat and landscape pattern indices in the Beijing-Tianjin-Hebei region from 2000 to 2018.

Stability of an anti-stroke peptide: driving forces and kinetics in chemical degradation.

NR2B9c (Lys-Leu-Ser-Ser-Ile-Glu-Ser-Asp-Val) is a 9-amino acid peptide that has been illustrated to be a potential anti-stroke drug. For more effective treatment, suitable drug delivery systems should be developed. However, little is known about the stability of NR2B9c which is essential to its formulation.

Formulation and characterization of hydrophilic drug diclofenac sodium-loaded solid lipid nanoparticles based on phospholipid complexes technology.

To successfully prepare the diclofenac sodium (DS)-loaded solid lipid nanoparticles (SLNs), phospholipid complexes (PCs) technology was applied here to improve the liposolubility of DS. Solid lipid nanoparticles (SLNs) loaded with phospholipid complexes (PCs) were prepared by the modified emulsion/solvent evaporation method. DS could be solubilized effectively in the organic solvents with the existence of phospholipid and apparent partition coefficient of DS in PCs increased significantly.

Preformulation study of methazolamide for topical ophthalmic delivery: physicochemical properties and degradation kinetics in aqueous solutions.

Methazolamide (MTZ) is an anti-glaucoma drug. The present paper aims to characterize the physicochemical properties and degradation kinetics of MTZ to provide a basis for topical ophthalmic delivery. With the increase in pH (pH 5.