MicroRNA-152 Targets Phosphatase and Tensin Homolog to Inhibit Apoptosis and Promote Cell Migration of Nasopharyngeal Carcinoma Cells.

BACKGROUND Nasopharyngeal carcinoma (NPC) is a type of head and neck cancer with very high prevalence in southern China. Phosphatase and tensin homolog (PTEN), a tumor suppressor, was reported to be downregulated in NPC patients and correlated with pathological grade and clinical stage of NPC. MATERIAL AND METHODS Luciferase reporter assay, qPCR, and Western blot analysis were used to determine if PTEN is a target of miR-152.

[Effects of nasal septum operation combined with naso sinus on prognosis of nasal septum surgery].

Objectives: To investigate the effet of nasal septum operation combined with nasal sinuses on postoperative nasal septum.

Method: Sixty-five patients with deflection of nasal septum complicating chronic sinusitis were underwent nasal septum and nasal sinus operations under nasal endoscope. Postoperative nasal septum recover were observed and compared with patients underwent only simple nasal septum operation.

[Evaluation of tympanoplasty with reconstruction of the external canal after mastoidectomy for cholesteatoma].

Objective: To investigate the method to repair the deletion of external canal and opened mastoid space after mastoidectomy.

Method: One stage tympanoplasty with reconstruction of the external canal with temporal cortex was completed in 58 cases (58 ears) with cholesteatoma.

Result: During the follow-up ranging from one to three years, there was only one relapse.