Retraction notice to "Autophagy regulates the Wnt/GSK3ß/ß-catenin/cyclin D1 pathway in mesenchymal stem cells (MSCs) exposed to titanium dioxide nanoparticles (TiO2NPs)" [Toxicol. Rep. 7C (2020) 1216-1222].

[This retracts the article DOI: 10.1016/j.toxrep.

Assessing public health and economic loss associated with black carbon exposure using monitoring and MERRA-2 data.

Black carbon (BC) exposure in China continues to be relatively high, prompting researchers to assess BC exposure levels using data from monitoring sites, satellite remote sensing, and models. However, data regarding the application of a combined strategy comprising the analysis of monitoring data and various types of data to simulate BC exposure levels are lacking. Hence, the current study seeks to estimate short- and long-term BC exposure levels by combining national monitoring data with data from the second Modern-Era Retrospective analysis for Research and Applications (MERRA-2).

Migrasome biogenesis and functions.

The migrasome is a newly discovered organelle produced by migrating cells. As cells migrate, long and thin retraction fibers are left in their wake. On these fibers, we discovered the production of a pomegranate-like structure, which we named migrasomes.

Autophagy regulates the Wnt/GSK3β/β-catenin/cyclin D1 pathway in mesenchymal stem cells (MSCs) exposed to titanium dioxide nanoparticles (TiONPs).

The application of titanium dioxide nanoparticles (TiONPs) is on the increase, and so the number of studies dedicated to describing this material's biological effects. Previous studies have presented results indicating the controversial impact of TiONPs on cell fate regarding death and survival. We speculate that this may be due to focusing on each of the subject cells as an isolated individual.

Computerized screening of G-protein coupled receptors to identify and characterize olfactory receptors.

Olfactory receptors (ORs) are a group of G protein coupled receptors (GPCRs) that initiate chemical odorant signals. Although ORs are predominantly located in nasal epithelia to detect smell, these receptors are also present in peripherally in non-nasal organs/tissues. Since the quality of life and cognitive and sensorial features of sense of smell are worsened in multiple chemical sensitivity due to the interaction of ORs with offending compounds, it is important to not only differentiate these receptors from other GPCRs but also characterize these organelles to understand the underlying mechanisms of smelling disorders.

Simulative structure and binding sites of lyral with olfactory receptor 10J5 using computational prediction methods.

Olfactory receptor (OR) genes are extensively distributed throughout the human organism. Although these receptors are predominantly located in the olfactory epithelium, binding between odorant chemicals and corresponding ORs initiates downstream events in other tissues. In particular, exposure to allergen fragrances results in the induction of contact dermatitis.

Computational prediction methods to simulate structure and binding sites of coumarin with olfactory receptor 5P3.

Olfactory receptor 5P3 is coded by OR5P3 gene in human OR5P3 and recognized as the receptor for coumarin present in 30% of fragrances and might adversely affect human health. OR5P3 are also associated with coumarin-related breast cancer development and acquired tamoxifen resistance in breast cancer cells. Previously various investigators noted that coumarin acts as a ligand for OR5P3 and binding of this molecule to OR5P3 leads to downstream changes in the olfactory bulb and central nervous system.

Molecular mechanisms underlying titanium dioxide nanoparticles (TiONP) induced autophagy in mesenchymal stem cells (MSC).

The bone marrow is one of the target tissues for titanium dioxide nanoparticles (TiONP) following environmental exposure. At present, the consequences of TiONP exposure in bone are not well known. The aim of this study was to investigate the effects of TiONP on mesenchymal stem cells (MSCs) and potential underlying mechanisms.

Terrestrosin D from attenuates bleomycin-induced inflammation and suppresses fibrotic changes in the lungs of mice.

Terrestrosin D (TED), from L. (Zygophyllaceae), exhibits anti-tumour and anti-inflammatory activities. However, its effects on bleomycin (BLM)-induced pulmonary inflammation and the subsequent fibrotic changes remain unclear.