Publications by authors named "Shun-Ming Yang"
Thiocyanate compounds are key intermediates in the synthesis of pharmaceuticals and other sulfur-containing organic compounds. Herein, we first report an electrochemical protocol to synthesize vinyl thiocyanates from decarboxylative coupling of cinnamic acids with NHSCN in aqueous solution. This method provides thiocyanation products with broad functional group tolerance under ambient conditions.
View Article and Find Full Text PDFGold nanoparticles as multimodality imaging agents for brain gliomas.
J Nanobiotechnology
November 2015
Article Synopsis
- Nanoparticles, specifically gold nanoparticles (AuNPs), are effective for targeted delivery in brain cancer therapy, facilitating high-resolution imaging for analyzing their transport from microvasculature to tumors.
- The study employed in vivo and post-mortem imaging techniques, revealing important details of the connection between glioma cells and the surrounding blood vessels while also showing leakage of AuNPs from tumor-associated microvessels.
- The findings suggest that AuNPs could enhance various imaging methods and successfully identified glioma cells, tracked tumor progression, and highlighted significant differences in nanoparticle leakage between tumor and normal vasculature.