Effects of Ginsenoside Rg1 Regulating Wnt/-Catenin Signaling on Neural Stem Cells to Delay Brain Senescence.

This is a study on the relationship between the protective effect of ginsenoside Rg1 on senescent neural stem cells and Wnt-/catenin signaling pathway. . Recent studies have shown that overactivation of the Wnt/-catenin signaling pathway is closely related to stem cell senescence.

[Research of anti-aging mechanism of ginsenoside Rg1 on brain].

Neurodegenerative disease is common and frequently occurs in elderly patients. Previous studies have shown that ginsenoside Rg1 was able to inhibit senescent of brain, but the mechanism on the brain during the treatment remains elucidated. To study the mechanism of ginsenoside Rg1 in the process of anti-aging of brain, forty male SD rats were randomly divided into normal group, Rg1 normal group, brain aging model group and Rg1 brain aging model group, each group with 10 rats (brain aging model group: subcutaneous injection of D-galactose (120 mg kg(-1)), qd for 42 consecutive days; Rg1 brain aging model group: while copying the same test as that of brain aging model group, begin intraperitoneal injection of ginsenosides Rg1 (20 mg x kg(-1)) qd for 27 d from 16 d.

[Biodegradability of extracellular polymeric substances (EPS) produced by aerobic granules].

Aerobic granules were cultivated with synthetic wastewater and were added in the course of aerobic starvation. Results showed that EPS produced by aerobic granules was composed of 40% biodegradable and 60% nonbiodegradable EPS. Among these, only biodegradable EPS could be utilized by their producers, while nonbiodegradable EPS contributed to maintain the spatial structures of aerobic granules.