This study explored the use of virtual reality (VR) in disaster preparedness education, focusing on VR scenarios, disaster types, and user interactivity to identify gaps in existing research. A scoping review methodology, based on the Arksey and O'Malley framework and Preferred Reporting Items for Systematic Reviews and Meta-Analyses-Scoping Reviews (PRISMA-ScR) guidelines, was used, and the protocols were registered in the UMIN Clinical Trials Registry (UMIN000052800). The review included PubMed, CINAHL, the Cochrane Central Register of Controlled Trials in the Cochrane Library, and Ichushi-Web of the Japan Medical Abstract Society, with data up to January 31, 2024.
View Article and Find Full Text PDFIntroduction: Patient safety incidents, including medical errors and adverse events, frequently occur in intensive care units, leading to a significant psychological burden on healthcare workers. This burden results in second victim syndrome, which impacts the psychological and psychosomatic well-being of these workers. However, a systematic review focusing specifically on this condition among intensive care unit healthcare workers is lacking.
View Article and Find Full Text PDFThe effects of surface loading of iridium(II) oxide (IrO), manganese(IV) oxide (MnO), and cobalt(II) phosphate (CoPi) on the rate of photocatalytic oxygen evolution by anatase or rutile titania particles suspended in aqueous solutions of an electron acceptor, iodate ions, were studied by light intensity-dependence (LID) kinetic analyses. Although the role of these deposits has been reported to be a cocatalyst without showing results of any kinetic analysis, the present LID kinetic study suggested that the deposits may act as a "positive-hole capturer" for oxygen evolution, not as a cocatalyst for both metal oxides and CoPi. Further studies on the effects of loading amount, deposit types, titania crystalline type, and titania-particle size on the reaction order were also performed by LID analysis based on the proposed kinetic model.
View Article and Find Full Text PDFWe report a methodology for creating protonated layered titanate-rutile heterojunctions on the outer particle surface of protonated layered titanate by treating layered potassium titanate (KTiLiO) with dilute HCl and then drying it at room temperature under reduced pressure. After Pt co-catalyst loading, this protonated layered titanate/rutile composite with heterojunctions showed higher photocatalytic H evolution activity from water under simulated solar light compared to that of Pt-loaded P25, the standard photocatalyst for this reaction. The high photocatalytic activity was ascribable to enhanced photocatalytic activity of the protonated layered titanate based on an efficient charge separation at the protonated layered titanate-rutile heterojunction in addition to the sensitization effects of rutile, which absorbs light with longer wavelengths compared to those of protonated layered titanate.
View Article and Find Full Text PDFWe recently reported a novel heme sensor using fluorescently labeled heme oxygenase-1; however, its inherent enzyme activity would be a potential obstacle in quantifying heme in biological samples. Here, we found that mutation of the catalytically important residue, Asp140, with histidine in the sensor not only diminished the heme degradation activity but also increased heme binding affinity. The sensor with a visible fluorophore was also found to be beneficial to avoid background emission from endogenous substance in biological samples.
View Article and Find Full Text PDFFree heme, the protein-unbound form of heme, has both toxic and regulatory effects on cells. To detect free heme at low concentrations, we developed a heme sensor using fluorescently labeled heme oxygenase-1 (HO-1), an enzyme that catalyzes oxidative heme degradation and has a high affinity for heme. The response of the heme sensor is based on the fluorescence quenching that occurs when heme binds to the enzyme.
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