Publications by authors named "Shun Uchida"

Background: Creating clinical vignettes requires considerable effort. Recent developments in generative artificial intelligence (AI) for natural language processing have been remarkable and may allow for the easy and immediate creation of diverse clinical vignettes.

Objective: In this study, we evaluated the medical accuracy and grammatical correctness of AI-generated clinical vignettes in Japanese and verified their usefulness.

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Background: An illness script is a specific script format geared to represent patient-oriented clinical knowledge organized around enabling conditions, faults (i.e., pathophysiological process), and consequences.

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Background: Medical history contributes approximately 80% to a diagnosis, although physical examinations and laboratory investigations increase a physician's confidence in the medical diagnosis. The concept of artificial intelligence (AI) was first proposed more than 70 years ago. Recently, its role in various fields of medicine has grown remarkably.

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Glioblastoma is the deadliest form of brain tumor. The presence of the blood-brain barrier (BBB) significantly hinders chemotherapy, necessitating the development of innovative treatment options for this tumor. This report presents the in vitro and in vivo efficacy of an antibody-drug conjugate (ADC) that targets glypican-1 (GPC1) in glioblastoma.

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Article Synopsis
  • ChatGPT, specifically its latest version GPT-4, has shown improvements in generating accurate and useful responses, particularly in English, though it still faces challenges generating reliable medical information in languages like Chinese and Japanese.
  • The study aimed to assess the accuracy of ChatGPT in providing medical knowledge and diagnoses based on the National Medical Licensing Examination (NMLE) questions from Japan.
  • By analyzing the text-based questions with two general practice physicians verifying the answers, the research seeks to determine the effectiveness of ChatGPT for Japanese healthcare inquiries.
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Background: Formative feedback plays a critical role in guiding learners to gain competence, serving as an opportunity for reflection and feedback on their learning progress and needs. Medical education in Japan has historically been dominated by a summative paradigm within assessment, as opposed to countries such as the UK where there are greater opportunities for formative feedback. How this difference affects students' interaction with feedback has not been studied.

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  • A study was conducted to evaluate the effectiveness of a clinical diagnostic support system (CDSS) compared to Google and a control group in aiding medical students with diagnostic accuracy based on patient histories.
  • In the study involving 64 medical students and 13 residents at Chiba University Hospital, students who used the CDSS (mean score of 12.0) and Google (mean score of 11.9) performed better than those in the control group (mean score of 9.5).
  • However, residents who did not use either resource achieved a higher mean score (14.7), indicating that more experienced individuals could still perform better than students using the CDSS or Google.
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  • The study compares the effectiveness of Hybrid problem-based learning (PBL) and Pure PBL in teaching clinical reasoning skills to 99 medical students at Chiba University Hospital.
  • Results showed no significant differences in students' perceived competence and satisfaction, but the Hybrid PBL group improved significantly in recalling differential diagnoses and practicing clinical reasoning processes.
  • Qualitative analysis identified 13 advantages of Hybrid PBL, highlighting benefits in knowledge acquisition, discussion facilitation, and feedback mechanisms.
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Background: Physicians frequently experience patients as difficult. Our study explores whether more empathetic physicians experience fewer patient encounters as difficult.

Objective: To investigate the association between physician empathy and difficult patient encounters (DPEs).

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Periventricular anastomosis in moyamoya disease (MMD) is an unusual angiographic finding that arises from perforating arteries such as the lenticulostriate artery (LSA), thalamic artery (THA), and anterior choroidal artery (AChA). This anastomosis is associated with increased hemorrhagic risk in MMD and can be corrected by direct revascularization surgery. The present supplementary analysis on a prospective cohort aimed to elucidate changes in periventricular anastomosis after indirect revascularization surgery alone for adult patients with misery perfusion due to ischemic MMD.

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Article Synopsis
  • Deep tendon reflexes (DTR) are essential skills for medical students, but many lack confidence in performing them, highlighting the need for effective training methods.
  • A study evaluated the effectiveness of a flipped classroom approach versus traditional instruction among 83 fifth-year medical students at Chiba University Hospital over several months.
  • The results showed that while students in the flipped classroom starting with higher pre-test confidence (2.8) compared to the control group (2.3), both groups had similar post-test confidence levels (3.9 vs. 4.1) and mastery scores (4.3 vs. 4.1), indicating that initial training might not influence long-term skill retention significantly.
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Objectives: Although revascularization surgery is recommended for adult patients with moyamoya disease (MMD) who present with ischemic symptoms due to hemodynamic compromise, the clinical course of such patients who are treated with medical management alone remains unclear. Here, we report outcomes of adult patients with cerebral misery perfusion due to ischemic MMD who received medical management alone.

Materials And Methods: We prospectively followed up patients who showed misery perfusion in the symptomatic cerebral hemisphere on O gas positron emission tomography (PET) and received strict medical management alone after refusing revascularization surgery.

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Introduction: Revascularization surgery for adult moyamoya disease (MMD) with ischemic presentation changes cognitive function and prevents further cerebral ischemic events. Most studies however repeated neuropsychological evaluation within 1 year after surgery. Our previous prospective cohort study of adult patients with MMD with misery perfusion who underwent direct revascularization surgery showed cognitive improvement and decline in 31% and 44%, respectively, of the patients 2 months after surgery.

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Peripheral ulcerative keratitis (PUK) is a non-infectious ulcer at the peripheral corneal stroma. Autoimmune diseases can cause PUK, but PUK caused by large vessel vasculitis (LVV) has rarely been reported. We report the case of a 71-year-old woman with complaints of low-grade fever and left eye pain.

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