Publications by authors named "Shumaila Nawaz Khan"
Article Synopsis
- Nasopharyngeal carcinoma (NPC) affects patients with bulky tumors and extensive lymph node involvement, often leading to poor prognosis, and this study focuses on evaluating the effectiveness and side effects of neoadjuvant chemotherapy followed by chemoradiotherapy for treating advanced cases of NPC.
- In this prospective study, patients aged 16-65 with stage III-IVA NPC were treated with either a combination of docetaxel, cisplatin, and fluorouracil or gemcitabine and cisplatin, with their treatment responses and haematological toxicity monitored post-therapy.
- Results showed that the group receiving gemcitabine and cisplatin had a higher complete response rate (71.9%) and lower partial
Induction followed by concurrent chemoradiation (CCRT) is the standard of care for locally advanced nasopharyngeal carcinoma (LANPC). This study evaluated and compared the efficacy of two regimens of neoadjuvant chemotherapy along with CCRT in LANPC. Patients with LANPC were randomly divided in Group I (receiving neoadjuvant gemcitabine and cisplatin) and Group II (receiving neoadjuvant docetaxil, cisplatin and fluorouracil).
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