Publications by authors named "Shuling Kang"
Background: The impact of heat waves and atmospheric oxidising pollutants on residential mortality within the framework of global climate change has become increasingly important.
Objective: In this research, the interactive effects of heat waves and oxidising pollutants on the risk of residential mortality in Fuzhou were examined. Methods We collected environmental, meteorological, and residential mortality data in Fuzhou from 1 January 2016, to 31 December 2021.
Background: Previous studies have found that lncRNA polymorphisms are associated with the prognosis of gastric cancer (GC), but the specific roles of many lncRNA polymorphism sites in gastric cancer are still unclear. Our study aims to deeply explore the relationship between genetic polymorphism of lncRNA and the prognosis of GC.
Methods: The genotypes of candidate SNP locus were detected by Sequenom Mass ARRAY SNP.
Impact of air pollutants on hospital visits for pediatric asthma in Fuzhou city, southeast China.
Environ Sci Pollut Res Int
August 2022
Rapid social development in China has resulted in severe air pollution and adverse impacts on people's health. Although studies have been conducted on the relationship between exposure to air pollutants and asthma exacerbation, most studies were performed in relatively heavily polluted areas, while little is known about the effect of air pollutants in less polluted areas. We assessed the effects of air pollutants on the risk of asthma-related outpatient and emergency visits of infants and children aged from 0 to 13 years during 2018 to 2020 in Fuzhou city, southeast China.
View Article and Find Full Text PDFStudies have shown inconsistent associations between serum uric acid (SUA) levels and mortality in peritoneal dialysis (PD) patients. We conducted this meta-analysis to determine whether SUA levels were associated with cardiovascular or all-cause mortality in PD patients. PubMed, Embase, Web of Science, the Cochrane Library, CNKI, VIP, Wanfang Database, and trial registry databases were systematically searched up to April 11, 2021.
View Article and Find Full Text PDFBackground: Metabolite genome-wide association studies (mGWAS) are key for understanding the genetic regulation of metabolites in complex diseases including cancers. Although mGWAS has revealed hundreds of metabolomics quantitative trait loci (mQTLs) in the general population, data relating to gastric cancer (GC) are still incomplete.
Methods: We identified mQTLs associated with GC by analyzing genome-wide and metabolome-wide datasets generated from 233 GC patients and 233 healthy controls.
Background: This case-control study investigated the role of Chlamydia pneumoniae (Cpn) infection in the pathogenesis of lung cancer and the combined and interaction effect of Cpn infection, smoking, and various environmental factors.
Methods: The study comprised 449 lung cancer patients and 512 age- and sex-matched healthy controls. All participants provided a 5 ml fasting peripheral venous blood sample for testing Cpn-specific IgG and IgA by using micro-immunofluorescence.
Background: Some studies showed that microRNA-497 (miR-497) might act as a prognostic biomarker of cancer. However, the conclusion was not consistent. The aim of this study was to investigate the prognostic role of miR-497 in various carcinomas.
View Article and Find Full Text PDFObjective: The etiology of lung cancer has been attributed to both environmental and genetic factors. In this study, we investigated the association between five miRNA gene single-nucleotide polymorphisms (SNPs) and the risk of lung cancer, and explored the interaction between genetic and environmental factors in the Han people of China, the ethnic group that represents >90% of the population of the country.
Methods: This case-control study included 1,067 cases and 1,085 controls.