Copper-Catalyzed Difluoromethylation of Alkenyl Thianthrenium Salts.

We have developed a novel and straightforward protocol that facilitates the transformation of alkenylsulfonium salts leading to the direct synthesis of -difluoromethylated alkenes. The success of this method relies on the use of copper catalysis and Vicic-Mikami reagent (DMPU)Zn(CFH). These mild protocols offer the advantage of selectively synthesizing either aromatic or aliphatic difluoromethylated alkenes.

The Effectiveness of Technology-Based Interventions for Reducing Loneliness in Older Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

To systematically analyze the effectiveness of technology-based interventions for reducing loneliness in older adults. We searched relevant electronic databases from inception to April 2021, which included Cochrane Library, PubMed, Web of Science, SpringerLink, EMBASE, CNKI, and Wanfang. The following criteria were used: (i) study design-randomized controlled trial (RCT) designs, (ii) people-older adults (aged ≥ 60 years), (iii) intervention-technology-based interventions in which a core component involved the use of technology to reduce loneliness in older adults; and (iv) outcome-reduction of loneliness level in terms of rating scale scores.