Synopsis of recent research by authors named "Shukun Yan"
- Shukun Yan's research primarily focuses on the regulatory mechanisms of AKT kinase, a critical player in cell metabolism and survival, particularly in the context of prostate cancer and metabolic diseases.
- In recent studies, Yan demonstrated that zinc ions can activate AKT kinase, promoting prostate cancer cell proliferation by disrupting its intramolecular interactions, highlighting the physiological role of zinc in cancer biology.
- Additionally, Yan identified XAF1 as an endogenous inhibitor of AKT, revealing its function in modulating AKT activation and suggesting potential implications for weight management and insulin sensitivity in metabolic conditions.