Comparative physico-chemical profiles of Tugaksheeree (Curcuma angustifolia Roxb. and Maranta arundinacea Linn.).

Tugaksheeree is as an ingredient in many Ayurvedic formulations. The starch obtained from the rhizomes of two plants, is used as Tugaksheeree, Curcuma angustifolia (CA) Roxb. (Family: Zingiberaceae) and Maranta arundinacea (MA) Linn.

Effect of Sameera Pannaga Rasa (arsenomercurial formulation) in the management of Tamaka Shwasa (bronchial asthma) - Randomized double blind clinical study.

Asthma represents a profound world-wide public health problem. The most effective anti-asthmatic drugs currently available include β2-agonists and glucocorticoids which can controls asthma in about 90-95% of patients. In Ayurveda, this miserable condition is comparable with Tamaka Shwasa type of Shwasa Roga.

Assessment of Lekhana Basti in the management of hyperlipidemia.

Hyperlipidemia is highly prevalent and is closely related to coronary heart disease which is the most common cause of death. Raised cholesterol is estimated to be responsible for 18% of cerebrovascular disease and 56% of ischemic heart disease. Overall, these diseases account for about 4.

Characteristics, composition and oxidative stability of Lannea microcarpa seed and seed oil.

The proximate composition of seeds and main physicochemical properties and thermal stability of oil extracted from Lannea microcarpa seeds were evaluated. The percentage composition of the seeds was: ash (3.11%), crude oil (64.

Analysis of heavy metals concentration in ambient air and in human population of Rohtak, India.

The samples of ambient air collected from six different sites of the city during three different seasons on glass fibre filter papers were estimated for selected metals. The maximum value of Pb (0.191 microg m-3), Cd (0.

Acute toxicity study of Vasaguduchyadi Kwatha: A compound Ayurvedic formulation.

Vasaguduchyadi Kwatha is a compound Ayurvedic formulation, indicated for the treatment of liver diseases, especially for Kamala (jaundice) and Panduroga (anemia). However, till date, no safety profile of this formulation has been reported; hence, in the present study, freshly prepared and market samples of Vasaguduchyadi Kwatha were evaluated for acute toxicity. Acute toxicity test was evaluated as per OECD 425 guidelines with 5 000 mg/kg as limit test in Wistar strain albino rats.

Pharmacognostical and Preliminary physicochemical evaluation of Triphaladi granules - A polyherbal Ayurvedic formulation.

Triphaladi Kwatha, a polyherbal Ayurvedic formulation, is recommended by Chakradatta and Yogaratnakara in the management of Prameha which has resemblance with type 2 diabetes mellitus. The present study deals with development of pharmacognostical and preliminary pharmaceutical profile of Triphaladi granules. The pH (5% aqueous extract) was 6.

Comparative effect of Navayasa Rasayana Leha and Medhya Rasayana tablet along with Dhatryadhyo Lepa in Ekkakushta (psoriasis).

All skin diseases can be included under the umbrella of Kushta Roga. Ekkakushta is a variety of Kshudra Kushtha with dominancy of Vata and Kapha Doshas. It is characterized by symptoms like- Aswedanam, Mahavastum, Matsyashakalopamam, etc.

Linear short histidine and cysteine modified arginine peptides constitute a potential class of DNA delivery agents.

The success of gene therapy relies on the development of safe and efficient multifunctional carriers of nucleic acids that can overcome extra- and intracellular barriers, protect the nucleic acid and mediate its release at the desired site allowing gene expression. Peptides bear unique properties that are indispensable for any carrier, e.g.

FT-IR, FT-Raman, NMR, UV and quantum chemical studies on monomeric and dimeric conformations of 3,5-dimethyl-4-methoxybenzoic acid.

Extensive spectroscopic investigations along with theoretical quantum chemical studies on 3,5-dimethyl-4-methoxybenzoic acid (DMMBA) have been consummated. The fundamental vibrational transitions were addressed by experimental FT-IR (4000-400cm(-1)) and FT-Raman (4000-10cm(-1)) techniques and density functional calculations at B3LYP/6-311++G(d,p) and B3LYP/6-311++G(df,pd) levels of theory. The (1)H, (13)C and DEPT 135 NMR spectra of studied compound were recorded in deuterated dimethylsulfoxide (DMSO-d6), and compared with computed data obtained by using gauge including atomic orbital (GIAO) method.

Predictors of diabetic retinopathy in patients with type 2 diabetes who have normoalbuminuria.

Background: Microalbuminuria is an independent predictor of retinopathy, so absence of microalbuminuria may tend clinician not to screen for diabetic retinopathy (DR).

Aim: The aim of our study was to estimate prevalence of DR in patients with type 2 diabetes who have normoalbuminuria, and to study predictors for DR, which can identify these high-risk individuals.

Subjects And Methods: In a prospective cross-sectional study that included patients with type 2 DM and normoalbuminuria.

Gene duplication, lineage-specific expansion, and subfunctionalization in the MADF-BESS family patterns the Drosophila wing hinge.

Gene duplication, expansion, and subsequent diversification are features of the evolutionary process. Duplicated genes can be lost, modified, or altered to generate novel functions over evolutionary timescales. These features make gene duplication a powerful engine of evolutionary change.

TFP5, a peptide derived from p35, a Cdk5 neuronal activator, rescues cortical neurons from glucose toxicity.

Multiple lines of evidence link the incidence of diabetes to the development of Alzheimer's disease (AD). Patients with diabetes have a 50 to 75% increased risk of developing AD. Cyclin dependent kinase 5 (Cdk5) is a serine/threonine protein kinase, which forms active complexes with p35 or p39, found principally in neurons and in pancreatic β cells.

Domination of volumetric toughening by silver nanoparticles over interfacial strengthening of carbon nanotubes in bactericidal hydroxyapatite biocomposite.

In order to address the problem of bacterial infections in bone-substitution surgery, it is essential that bone replacement biomaterials are equipped with bactericidal components. This research aims to optimize the content of silver (Ag), a well-known antibacterial metal, in a multiwalled carbon nanotube (CNT) reinforced hydroxyapatite (HA) composite, to yield a bioceramic which can be used as an antibacterial and tough surface of bone replacement prosthesis. The bactericidal properties evaluated using Escherichia coli and Staphylococcus epidermidis indicate that CNT reinforcement supports growth of Gram negative E.

Analgesic activity of Nelsonia canescens (Lam.) Spreng.root in albino rats.

Present study was undertaken to evaluate analgesic activity of root of Nelsonia canescens (Lam.) Spreng, a folklore medicinal plant used as the one of the source plant of Rasna. Study was carried out at two dose levels (270 mg/kg and 540 mg/kg) in albino rats.

Evaluation of anti-hyperlipidemic activity of Lekhana Basti in albino rats.

Lekhana Basti (medicated enema) is a Tikshna formulation which is basically aimed for Apatarpana of the body. The present study (medicated enema) was undertaken to evaluate its anti-hyperlipidemic activity in diet-induced hyperlipidemia animals. Parameters like changes in body weight, organ weight, serum total cholesterol, serum triglyceride, serum HDL cholesterol, and serum (LDL + VLDL) cholesterol were studied to assess the effect of therapy in comparison to the control groups.

In vitro antioxidant activity of hydro alcoholic extract from the fruit pulp of Cassia fistula Linn.

The present study is aimed to investigate antioxidant activity of the extracts of Cassia fistula Linn. (Leguminosae) fruit pulp. Cassia fistula Linn.

Phytochemical evaluation of the wild and cultivated varieties of Eranda Mula (Roots of Ricinus communis Linn.).

In Ayurveda, the roots of Eranda (Ricinus communis Linn.) are used in the treatment Amavata (rheumatism), Sotha (inflammation), Katisula (backache), Udararoga (disease of abdomen), Jwara (fever), etc, Due to high demand, root of the cultivated variety is mainly used in place of wild. But, a comparative phytochemical profile of both varieties is not available till date.

A role for IRF8 in B cell anergy.

B cell central tolerance is a process through which self-reactive B cells are removed from the B cell repertoire. Self-reactive B cells are generally removed by receptor editing in the bone marrow and by anergy induction in the periphery. IRF8 is a critical transcriptional regulator of immune system development and function.

In vitro evaluation of antioxidant activity of Cordia dichotoma (Forst f.) bark.

Cordia dichotoma Forst. f. bark, identified as botanical source of Shleshmataka in Ayurvedic pharmacopoeia.

A comparative pharmacognostical and preliminary physico-chemical analysis of stem and leaf of Bacopa monnieri (L.) Pennel and Bacopa floribunda (R.BR.) Wettst.

Brahmi is a well-known herbal drug having an effect on brain as a memory enhancer. Bacopa monnieri (L.) Pennel and Bacopa floribunda (R.

Pharmacognostical evaluation of Launaea sarmentosa (Willd.) schultz-bip.ex Kuntze root.

Launaea sarmentosa (Willd) Schultz-Bip.ex Kuntze (Asteraceae), locally known as Kulhafila in the Maldives, is a creeping herb, native to tropical Indian coastlines. According to anecdotal evidence from locals in the Maldives, the roots of this plant are used as an ingredient of a popular medicinal preparation (Hilibeys) taken by mothers after childbirth.

Efficacy of Virechana and Basti Karma with Shamana therapy in the management of essential hypertension: A comparative study.

Considering high prevalence and the need to look for alternative medicine, essential hypertension was screened in light of Vata-Pitta Pradhana Rakta Pradoshaja Vikara as mentioned by Acharya Charaka. Comparing the etiological factors, symptomatology, and complications with Rakta Pradoshaja Vikara with that of essential hypertension, a striking similarity was revealed. To prove the practical approach of management of Vata-Pitta Pradhana Rakta Pradoshaja Vikara, a randomized open clinical trial on 33 uncomplicated subjects of essential hypertension was conducted.

Clinical efficacy of Eranda Muladi Yapana Basti in the management of Kati Graha (Lumbar spondylosis).

Low back pain affects approximately 60.85% of adults during some point of their life and 10% of this is because of Lumbar Spondylosis (LS). Kati Graha which is correlated with LS is a degenerative condition affecting the discs, vertebral bodies, and/or associated joints of the lumbar spine.