Publications by authors named "Shuk Yan Joey Leung"
Front Neurosci
January 2023
Article Synopsis
- Schizophrenia (SCZ) is a complex mental health disorder influenced by genetic factors, with studies revealing a gap in understanding due to undetected medium-sized structural variants (SVs).
- The research aimed to identify these SVs in families with chronic SCZ characterized by severe negative symptoms and cognitive deficits.
- By using advanced third-generation sequencing techniques, the study discovered 88 SVs associated with 79 genes, linking them to important brain functions and development pathways, which could help explain some aspects of the heritability of SCZ.
