Holographic multiplexing recording with an orthogonal polarized array.

This study combines tensor polarization holography theory and multichannel recording techniques and proposes a novel polarization encoding method, the orthogonal polarized array (OPA). This method can efficiently and independently reconstruct polarization holograms using accurate OPA waves in the reference-based multiplexing technique when the reference waves in the reading process have the same polarization state as those in the recording process. The novelty is that the multiplexing dimensions of the OPA can reach any number without limitations.

A RuNPs-based multifunctional nanoplatform with excellent dual enzyme-mimic activities for diabetes diagnosis, cancer cell elimination, and in vitro antibacterial.

Designing innovative nanozymes with satisfactory catalytic activity and biocompatibility through simple and inexpensive approaches and excavating their multifunctional applications have crucial value and significance for the development of nanozyme science. In this work, RuNPs with excellent oxidase (OXD)-mimetic and peroxidase (POD)-like activity were synthesized via simple one-pot solvothermal reaction and exploited for disease marker detection, elimination of cancer cells, and in vitro antibacterial. Based on the OXD-mimetic activity of RuNPs, a new colorimetric biosensor was ingeniously designed for α-glucosidase (α-Glu) activity determination and screening of its inhibitors.

Orthogonality of polarization superposition based on polarization holography.

We propose a polarization superposition orthogonal theory based on tensor polarization holography. Based on this theory, the holographic multiplexing capability can be improved measurably. The orthogonality of polarization waves is characterized by the null reconstruction in polarization holography, achieved through the superposition of multiple basic polarization reference waves.

Polarization evolution on higher and hybrid-order Poincaré spheres with coaxial polarization holograms.

Based on the tensor polarization holography theory, we propose a simple and convenient method in the recording material, phenanthrenequinone-doped polymethylmethacrylate, to generate beams on higher and hybrid-order Poincaré spheres, and realize their polarization evolution on the spheres by combining the recorded phase with the Pancharatnam-Berry phase. By simultaneously adjusting the polarization azimuth angle and relative phase of the recorded waves, independent phase-shifts can be imparted onto two orthogonal circular polarization states in reconstruction process of polarization holography. The beams on basic Poincaré sphere are transformed into that on arbitrary higher or hybrid-order Poincaré spheres.

A nanozyme multifunctional platform based on iron doped carbon dots derived from Tibetan Ganoderma lucidum waste for glucose sensing, anti-counterfeiting applications, and anticancer cell effect.

Implementing the concept of turning waste into treasure, the conversion of biomass waste into high-value carbon materials, especially carbon dots (CDs), has pointed out a new direction for disease diagnosis, tumor treatment, and other aspects. In this work, we have reported the GL-CDs(Fe) via a simple synthesis route exploiting Ganoderma lucidum waste as the precursor. Thanks to their excellent optical property and peroxidase mimetic activity, a novel GL-CDs(Fe)-based ratio fluorescence/colorimetric/smartphone triple mode sensing platform is cleverly fabricated for glucose determination with the LOD of 0.

Cheap and portable paper chip with terrific oxidase-like activity and SERS enhancement performance for SERS-colorimetric bimodal detection of intracellular glutathione.

Glutathione (GSH) acts a crucial role in the normal operation of manifold life activities and is closely bound up with many human diseases. Here, a SERS-colorimetric bimodal paper-based biosensor based on Mn-doped CDs/silver nanoparticles (Mn-CDs/AgNPs) has been fabricated for high-efficiency quantification of intracellular GSH. The Mn-CDs/AgNPs with fine oxidase-like characteristic and SERS enhancement ability has been assembled onto the Whatman filter paper (WFP) to cleverly fabricate paper chip (Mn-CDs/AgNPs@WFP) which can trigger the oxidation of colorless 3,3',5,5'-tetramethylbenzidine (TMB) into blue TMBox and simultaneously enhance the SERS signal of TMBox.

Scalar vortex beams produced by Pancharatnam-Berry phase optical elements that utilize polarization holography.

We discuss the appearance of the Pancharatnam-Berry phase in polarization holography, and confirm the possibility of generating scalar vortex beams by using the Pancharatnam-Berry phase. The polarization holograms used to generate scalar vortex beams are produced in phenanthrenequinone-doped polymethylmethacrylate (PQ/PMMA), where each radial direction consists of an equivalent half-wave plate hologram with gradually changing directions. The spin angular momentum carried by a circular polarization reading wave is converted into orbital angular momentum in a reconstruction process, resulting in the formation of scalar vortex beams with positive and negative topological charges controlled by the reading polarization.

Circular polarization detector based on polarization holography.

We propose and experimentally demonstrate the generation of a circular polarization detector based on planar polarization holography. The detector is designed by constructing the interference field according to the null reconstruction effect. We create multiplexed holograms, which feature the combination of two sets of hologram patterns and operate with opposite circular polarization beams.

Recent Research Progress of Surface-Enhanced Raman Scattering Dominated Analysis Strategies in Early Diagnosis of Diseases.

Timely and powerful diagnostic means can achieve better therapeutic effects, reduce disease torment, and improve survival rate. As a powerful non-invasive spectroscopy technology, surface-enhanced Raman scattering (SERS) have testified to be a great potential candidate for extensive early clinical disease diagnosis. In recent years, the introduction of SERS label, combined with other analysis modes or artificial intelligence, and the emergence of miniaturized devices have made SERS technology more advantageous in early diagnosis of diseases.

Construction of fluorescence and colorimetric tandem dual-mode sensor by modulating fluorescence and oxidase-like activity via valence switching of cerium-based coordination polymer nanoparticles for sarcosine detection.

A fluorescence and colorimetric tandem dual-mode sensor was established by modulating fluorescence and oxidase-like activity via valence switching of cerium-based coordination polymer nanoparticles (Ce-CPNs) for the detection of sarcosine (Sar) which is considered as a potential biomarker for the diagnosis of prostate cancer (PCa). In the present research, sarcosine oxidase (SOX) specifically catalyzes the oxidation of Sar to yield HO which can rapidly oxidize Ce(III)-CPNs to generate Ce(IV)-CPNs in appropriate alkaline solution. The generated Ce(IV)-CPNs create a markedly weakened fluorescent signal at 350 nm, while they can induce oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) to generate blue TMBox through emerging good oxidase-like activity.

A dual-mode ratiometric fluorescence and smartphone-assisted colorimetric sensing platform based on bifunctional Fe,Co-CQD for glucose analysis at physiological pH.

Diabetes is a common and fatal chronic metabolic disease characterized by hyperglycemia, and thus monitoring blood glucose level is essential for early screening and timely control of disease. Herein, we have prepared the bifunctional iron and cobalt co-doped carbon quantum dot (Fe,Co-CQD) with good optical properties and peroxidase-mimetic catalytic activity toward specific substrate o-phenylenediamine (OPD) under alkaline condition. Glucose oxidase (GOx) specifically catalyzes the oxidation of glucose into HO, and Fe,Co-CQD subsequently triggers a reaction between HO and OPD to form yellow product DAP with a distinct UV absorption peak at 420 nm.

regulated by Huang-Qi-Ling-Hua-San is a key factor by which to improve type 2 diabetes.

There is a lot of evidence that oral hypoglycemic drugs work by affecting gut microbes, but the key strains responsible for this effect are not well known. Huang-Qi-Ling-Hua-San (HQLHS), composed of , , , and L., is a specially designed Chinese medicine formula to treat type 2 diabetes (T2D).

Simple method for generating special beams using polarization holography.

Vector vortex beams are a kind of special beam that simultaneously carry spin and orbital angular momentum. The generation of vector vortex beams usually requires a complex and expensive optical system, which becomes a bottleneck hindering its further application. Thus, a compact, low-cost and efficient special beam generation system is demanded.

Image-free classification of fast-moving objects using "learned" structured illumination and single-pixel detection.

Object classification generally relies on image acquisition and subsequent analysis. Real-time classification of fast-moving objects is a challenging task. Here we propose an approach for real-time classification of fast-moving objects without image acquisition.

Mitotic-Spindle Organizing Protein MztA Mediates Septation Signaling by Suppressing the Regulatory Subunit of Protein Phosphatase 2A-ParA in .

The proper timing and positioning of cytokinesis/septation is crucial for hyphal growth and conidiation in . The septation initiation network (SIN) components are a conserved spindle pole body (SPB) localized signaling cascade and the terminal kinase complex SidB-MobA, which must localize on the SPB in this pathway to trigger septation/cytokinesis. The regulatory subunit of phosphatase PP2A-ParA has been identified to be a negative regulator capable of inactivating the SIN.