Heavy Cigarette Smokers in a Chinese Population Display a Compromised Permeability Barrier.

Cigarette smoking is associated with various cutaneous disorders with defective permeability. Yet, whether cigarette smoking influences epidermal permeability barrier function is largely unknown. Here, we measured skin biophysical properties, including permeability barrier homeostasis, stratum corneum (SC) integrity, SC hydration, skin surface pH, and skin melanin/erythema index, in cigarette smokers.

Comparison of publication trends in dermatology among Japan, South Korea and Mainland China.

Background: We previously showed that the number of publications in dermatology is increasing year by year, and positively correlates with improved economic conditions in mainland China, a still developing Asian country. However, the characteristics of publications in dermatology departments in more developed Asian countries such as Japan and South Korea are unknown.

Methods: In the present study, publications from 2003 through 2012 in dermatology in Japan, South Korea and mainland China were characterized.

Ten-year publication trends in dermatology in mainland China.

Background: China has been experiencing huge changes in all aspects, including dermatologic research, since its reform in 1978. However, it is not known how the economic and intellectual development has influenced the publication trends in the field of dermatology, which could mirror the scientific development in other medical disciplines. In the present study, we analyzed publication trends from dermatology departments in mainland China from 2002 to 2011.

Cutaneous resonance running time varies with age, body site and gender in a normal Chinese population.

Background/objectives: One phenomenon of skin aging is loss of cutaneous elasticity. Measurement of cutaneous resonance running time (CRRT) is a method to assess skin elasticity. Yet, information regarding the directional changes of CRRT associated with age, body sites and gender is not yet available.

Stratum corneum acidification is impaired in moderately aged human and murine skin.

Aged skin commonly is afflicted by inflammatory skin diseases or xerosis/eczema that could be triggered or exacerbated by impaired epidermal permeability barrier homeostasis. This defect is linked to reduced epidermal lipid synthesis in humans and in mice of advanced age (i.e.