The study investigates the relationship between blood pressure (systolic and diastolic) and cardiovascular disease (CVD) specifically in individuals without major cardiovascular risk factors.
A large cohort of 36,042 participants was analyzed, focusing on those with optimal glycemic and lipid profiles, over a follow-up period to assess the development of CVD.
Results showed a significant linear increase in CVD risk for higher blood pressure levels, with specific hazard ratios indicating increased risk associated with certain systolic (110-139 mm Hg) and diastolic (80-89 mm Hg) blood pressure ranges compared to lower levels.