Neuropsychiatr Dis Treat
January 2025
Purpose: Tic disorders are neurodevelopmental disorders characterized by movements or vocalizations, often accompanied by anxiety symptoms. However, the relationships between tic severity, age, and anxiety symptoms remain unclear. Here, we investigated the association between tic severity and age and examined how anxiety symptoms might influence this relationship.
View Article and Find Full Text PDFBackground: Gilles de la Tourette syndrome (GTS) is a persistent neurological disorder that profoundly affects the quality of life for afflicted individuals, however, tailored health-related quality of life (QOL) measures for Chinese pediatric GTS patients are lacking. This pioneering study aims to develop a QOL scale for Chinese children with GTS.
Methods: A cohort of 1,121 children (aged 6-16 years) diagnosed with GTS participated in scale development.
Cognitive Disengagement Syndrome (CDS) is a cluster of behavioral problems that severely affect an individual's functioning. Currently, there is no consensus on the main clinical features of CDS, and further exploration in large samples is needed. Using a cluster-stratified random sampling method, 72,106 children and adolescents were recruited from five provinces in mainland China for this study.
View Article and Find Full Text PDFThe aim of this study is to address the limitations in reconstructing the electrical activity of the heart from the body surface electrocardiogram, which is an ill-posed inverse problem. Current methods often assume values commonly used in the literature in the absence ofknowledge, leading to errors in the model. Furthermore, most methods ignore the dynamic activation process inherent in cardiomyocytes during the cardiac cycle.
View Article and Find Full Text PDFBackground: Children and adolescents are vulnerable to various psychiatric disorders during the critical phase of individual development. In China, the child behavior checklist (CBCL) is a widely employed psychometric questionnaire for assessing children and adolescents. However, further validation of the psychometric properties and diagnostic effectiveness of the CBCL DSM-oriented scales is necessary.
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