Strong binding and shrinkage of single and double (K) nuclear systems (K(-)pp, K(-)ppn, K(-)K(-)p and K(-)K(-)pp) predicted by Faddeev-Yakubovsky calculations.

Non-relativistic Faddeev and Faddeev-Yakubovsky calculations were made for K(-)pp, K(-)ppn, K(-)K(-)p and K(-)K(-)pp kaonic nuclear clusters, where the quasi bound states were treated as bound states by employing real separable potential models for the K(-)-K(-) and the K(-)-nucleon interactions as well as for the nucleon-nucleon interaction. The binding energies and spatial shrinkages of these states, obtained for various values of the K interaction, were found to increase rapidly with the K interaction strength. Their behaviors are shown in a reference diagram, where possible changes by varying the K interaction in the dense nuclear medium are given.

Topical diquafosol for patients with obstructive meibomian gland dysfunction.

Aims: To evaluate the effect of topical diquafosol in patients with meibomian gland dysfunction (MGD) using tear film parameters and quantitatively analyse the meibomian gland morphology.

Subjects And Methods: The subjects were 19 eyes of 10 patients diagnosed with obstructive MGD. All subjects were given 3% diquafosol ophthalmic solution with instructions to use one drop four times a day.

A newly developed noninvasive and mobile pen-shaped meibography system.

Purpose: To examine the usefulness of a newly developed noninvasive mobile pen-shaped meibography system.

Methods: This study evaluated a newly developed noninvasive mobile pen-shaped meibography system comprising an infrared light-emitting diode as the light source and a highly sensitive complementary metal oxide semiconductor image camera. The images were recorded digitally.

Comparison of the long-term effects of various topical antiglaucoma medications on meibomian glands.

Purpose: To examine the effects of long-term antiglaucoma eye drop treatment on meibomian glands.

Methods: The subjects were 71 eyes of 71 glaucoma patients (group 1) receiving one type of antiglaucoma eye drops, 61 eyes of 61 glaucoma patients (group 2) receiving two types of antiglaucoma eye drops, and 30 eyes of 30 glaucoma patients (group 3) receiving three types of antiglaucoma eye drops. Controls comprised 75 eyes of 75 healthy volunteers.

Effects of long-term topical anti-glaucoma medications on meibomian glands.

Objective: To examine effects of long-term topical anti-glaucoma medications on meibomian gland morphology and function and assess their relationship with slit-lamp findings.

Methods: This was a cross-sectional observational case series of 31 patients with glaucoma (mean age ± standard deviation, 65.0 ± 13.

Caffeine increases tear volume depending on polymorphisms within the adenosine A2a receptor gene and cytochrome P450 1A2.

Purpose: The primary aim of the present study was to examine the effect of caffeine on tear volume. The secondary aim was to investigate the relation between caffeine-induced changes in tear volume and polymorphisms in ADORA2A and CYP1A2.

Design: Double-masked, placebo-controlled, crossover study.

Association of contact lens-related allergic conjunctivitis with changes in the morphology of meibomian glands.

Purpose: To observe morphological changes in the meibomian glands of patients with contact lens-related allergic conjunctivitis (CLAC) and to assess the relations between the morphological changes and eyelid and tear film parameters.

Methods: We observed subjects in four groups: 64 eyes of 64 contact lens (CL) wearers with CLAC, 77 eyes of 77 CL wearers without CLAC, 55 eyes of 55 patients with perennial allergic conjunctivitis (perennial AC), and 47 eyes of 47 healthy volunteers. The following tests were performed: slit-lamp examination, measurement of tear film breakup time, grading of morphological changes in meibomian glands (meiboscore) as assessed by noncontact meibography, grading of meibomian gland distortion in meibography, tear production as assessed by Schirmer's I test, and grading of meibum expression.

Proposed diagnostic criteria for seborrheic meibomian gland dysfunction.

Purpose: To compare clinical findings between patients with seborrheic meibomian gland dysfunction (MGD) and normal controls and to propose diagnostic criteria for seborrheic MGD.

Methods: Thirty eyes of 30 patients [13 men and 17 women; age (mean +/- SD) 73.9 +/- 9.

Meibomian gland duct distortion in patients with perennial allergic conjunctivitis.

Purpose: To observe morphologic changes of meibomian glands in patients with and without perennial allergic conjunctivitis (AC) and to assess the relation between morphologic changes of the meibomian glands of both eyelids and tear film parameters.

Methods: In this study, 55 eyes of 55 patients with perennial AC and 47 eyes of 47 healthy volunteers as controls were included. The following tests were performed: a slit-lamp examination, measurement of tear film breakup time, grading of meibomian gland morphologic changes (meibography score) assessed with a noncontact meibography, meibomian gland duct distortion in meibography, tear production by the Schirmer I test, and grading of meibum expression.