Effects of different sperm sources on the clinical outcomes of oocyte maturation cycles combined with intracytoplasmic sperm injection.

Objectives: To evaluate the embryonic developments and clinical outcomes of different sperm sources with cycles of intracytoplasmic sperm injection (ICSI) and maturation (IVM).

Methods: This retrospective study was approved by the hospital ethics committee and conducted in the hospital fertilization (IVF) clinic. From January 2005 to December 2018, 239 infertile couples underwent IVM-ICSI cycles and were divided into three groups according to different sperm sources.

Chromosome aneuploidy analysis in embryos derived from in vivo and in vitro matured human oocytes.

Background: In vitro oocyte maturation (IVM) is being increasingly approached in assisted reproductive technology (ART). This study aimed to evaluate the quality of embryos generated by in-vitro matured immature follicles, as a guideline for further clinical decision-making.

Methods: A total of 52 couples with normal karyotypes underwent in vitro fertilization, and 162 embryos were donated for genetic screening.

Relation between the testicular sperm assay and sex hormone level in patients with azoospermia induced by mumps.

This study aimed to investigate the relation between the testicular sperm assay (TESA) and sex hormone level or testicular volume in patients with azoospermia induced by mumps. Samples from 52 patients with mumps-induced azoospermia were subjected to TESA, and then the sperm activity was observed microscopically. The sex hormone level was detected with an electrochemical assay, and ultrasound was used to calculate the testicular volume.

Effects of androgen on immunohistochemical localization of androgen receptor and Connexin 43 in mouse ovary.

Androgens have essential roles in the regulation of follicular development and female fertility. Androgen excess is the leading defect in polycystic ovary syndrome (PCOS) patients and involved in the ovarian dysfunction. The aim of this study was to elucidate the regarding regulatory role of androgen in the follicular development of female mouse.

HPV16E7-specific siRNA inhibits cell proliferation in CaSki cells.

High-risk human papilloma virus (HPV) infection is the main cause for the genesis of cervical carcinomas. After infection, E6 and E7 genes of HPV were integrated to the genome of the cervical epithelium. Continued expression of the transforming oncoproteins E6 and E7 not only drives the neoplastic progression in cervical epithelium, but also plays an important role in maintaining the malignant phenotype of cervical cancer cells.

Infertility treatment for azoospermic patients with a history of infectious parotitis (mumps) using combined techniques.

Purpose: The purpose of this study was to investigate the clinical efficacy of in vitro maturation-intracytoplasmic sperm injection (IVM-ICSI) technique on the treatment of azoospermic patients with a history of infectious parotitis (mumps).

Methods: Spermatozoa were obtained from the testes of azoospermic patients with a history of mumps and fertilized by ICSI. Eggs were retrieved from the spouse of patients in the natural cycle.

[Activation of astrocytes effects changes of substance P in cornu dorsal medullae spinalis in chronic prostatitis rats].

Objective: To explore the changes of substance P in cornu dorsal medullae spinalis effected by activation of astrocytes in rats with pain from chronic prostatitis.

Methods: Sixty SD rats were randomized into three groups: the control group (n=20), the chronic prostatitis pain model group (n=20) and the interference group (n=20). The model was induced by injection of complete Freund adjuvant and 3% carrageenan into the prostate.