Publications by authors named "Shuirong He"
MicroRNAs (miRNAs), a class of endogenous small RNAs with lengths of approximately 19-24 nucleotides, play important regulatory roles in cells. In recent years, miR-363 has emerged as a prominent member of the miR-92a family, participating in various biological functions, including cellular proliferation, cycle, migration, and apoptosis. In particular, miR-363 plays a critical role in acute kidney injury, renal fibrosis, and diabetic nephropathy and can serve as a biomarker for the diagnosis of renal cell carcinoma.
View Article and Find Full Text PDFBackground: Heavy metal exposure is an important cause of reduced bone mineral density (BMD). Epidemiological studies focusing on the effects of mixed heavy metal exposure on BMD in middle-aged and older people are scarce. In single-metal studies, men and women have shown distinct responses of BMD to environmental metal exposure.
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- Occupational chronic cadmium poisoning (OCCP) leads to serious and irreversible organ damage, and currently, there are no effective treatments or reliable biomarkers to assess recovery.* -
- A study analyzed urine samples from OCCP patients and healthy controls using advanced mass spectrometry techniques, revealing 66 metabolites with significant differences between the two groups.* -
- Among the findings, elevated urinary creatine levels showed promise as a sensitive biomarker for diagnosing and monitoring OCCP, outperforming other metabolites like glutamic acid and quinolinic acid.*