Stacking Ensemble Learning-Based [F]FDG PET Radiomics for Outcome Prediction in Diffuse Large B-Cell Lymphoma.

This study aimed to develop an analytic approach based on [F]FDG PET radiomics using stacking ensemble learning to improve the outcome prediction in diffuse large B-cell lymphoma (DLBCL). In total, 240 DLBCL patients from 2 medical centers were divided into the training set ( = 141), internal testing set ( = 61), and external testing set ( = 38). Radiomics features were extracted from pretreatment [F]FDG PET scans at the patient level using 4 semiautomatic segmentation methods (SUV threshold of 2.

Positron Emission Tomography Molecular Imaging for Phenotyping and Management of Lymphoma.

Positron emission tomography (PET) represents molecular imaging for non-invasive phenotyping of physiological and biochemical processes in various oncological diseases. PET imaging with F-fluorodeoxyglucose (F-FDG) for glucose metabolism evaluation is the standard imaging modality for the clinical management of lymphoma. One of the F-FDG PET applications is the detection and pre-treatment staging of lymphoma, which is highly sensitive.

High-resolution pediatric age-specific F-FDG PET template: a pilot study in epileptogenic focus localization.

Background: PET imaging has been widely used in diagnosis of neurological disorders; however, its application to pediatric population is limited due to lacking pediatric age-specific PET template. This study aims to develop a pediatric age-specific PET template (PAPT) and conduct a pilot study of epileptogenic focus localization in pediatric epilepsy.

Methods: We recruited 130 pediatric patients with epilepsy and 102 age-matched controls who underwent F-FDG PET examination.