Publications by authors named "Shuichiro Kurita"

Article Synopsis
  • The study explores the impact of remimazolam, a new anesthetic, on motor-evoked potentials (MEPs) during general anesthesia in patients undergoing spinal fusion surgery.
  • Ten adult patients were monitored with varying doses of remimazolam to determine whether higher doses affected MEP amplitude.
  • Results indicated no significant difference in MEP amplitude after increasing the dose, suggesting remimazolam may have a minimal impact on these electrical signals in the brain.
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Background: Yokukansan, a traditional Japanese medicine (Kampo), has been widely used to treat neurosis, dementia, and chronic pain. Previous in vitro studies have suggested that Yokukansan acts as a partial agonist of the 5-HT receptor, resulting in amelioration of chronic pain through inhibition of nociceptive neuronal activity. However, its effectiveness for treating postoperative pain remains unknown, although its analgesic mechanism of action has been suggested to involve serotonin and glutamatergic neurotransmission.

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Background: Dexamethasone is used perioperatively as an antiemetic for postoperative nausea and vomiting. Evidence and mechanism linking dexamethasone and hypertensive attack of pheochromocytoma during anesthesia have not been reported.

Case Description: We report a case of a hypertensive attack during anesthetic induction immediately after dexamethasone administration in a 35-year-old woman with adrenal pheochromocytoma.

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