Publications by authors named "ShuiLin Chen"

Background: The factors influencing the clinical outcome of arthroscopic rotator cuff repair are not fully understood.

Purpose: To explore the factors related to the postoperative outcome of arthroscopic single-row rivet rotator cuff repair in patients with rotator cuff injury and to construct the related nomogram risk prediction model.

Methods: 207 patients with rotator cuff injury who underwent arthroscopic single-row rivet rotator cuff repair were reviewed.

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Background: Frozen shoulder (FS) and Dupuytren's disease (DD) are two closely related diseases, but the mechanism of their interaction is unknown. Our study sought to elucidate the molecular mechanism of these two diseases through shared gene and protein interactions.

Methods: GSE75152 and GSE140731 data were downloaded from the Gene Expression Omnibus (GEO) database, and shared genes between FS and DD were selected by using R packages.

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  • This study explores the role of N6-methyladenosine (mA) modification in the immune microenvironment of osteoarthritis (OA), revealing significant differences in mA regulator expression between healthy and OA samples.
  • Researchers analyzed 139 OA samples to identify two mA modification patterns, key mA regulators, and their associations with immune cell infiltration and gene activity.
  • The findings suggest that mA modification influences OA progression and immune responses, providing new insights into the disease's underlying mechanisms.
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This study aims to explore the influence of organizational learning and dynamic capability on organizational performance of human resource service enterprises with the moderating role of technology environment and market environment. Data were gathered from 360 human resource service enterprises, and applied the hierarchical linear regression method and structural equation model to test the hypotheses. We found that organizational learning has a significantly positive impact on resource integration capability, as well as has a significantly positive impact on resource reconfiguration capability of human resource service enterprises.

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Happiness is the eternal pursuit of mankind and is also the ultimate goal of social governance and national development. Based on data from the Chinese General Social Survey, this study used a structural equation model to analyze the influence of social class identity and public service satisfaction on the happiness of residents. The effect of public service satisfaction and social trust between social class identity and residents' happiness was tested using the Monte Carlo method.

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Background: To systematically evaluate the efficacy of teriparatide and bisphosphonates in preventing fractures in postmenopausal women with osteoporosis.

Materials And Methods: We performed a systematic search of PubMed, Embase, and the Cochrane Library for randomized controlled trials (RCTs) that compared teriparatide and bisphosphonates for osteoporosis treatment. Searches were performed without language restrictions and included studies from beginning of time to March 2019.

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  • The research explores the relationship between corporate environmental responsibility (CER) and environmental performance (EP) in China's A-share chemical industry from 2006 to 2017 using the GMM model.
  • It finds that while CER has a positive but insignificant impact on EP, EP significantly enhances CER, suggesting a reciprocal relationship.
  • Additionally, the study reveals a nonlinear (inverted "U" shape) relationship between CER and EP, emphasizing the importance of fostering competitive market conditions to improve environmental performance in the sector.
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  • Metabolomics is used to investigate how herbal medicine, specifically Epimedium, can help treat osteoporosis (OP), but its exact mechanisms are not fully understood.
  • A study analyzed the effects of ethanol extract from Epimedium on OP in rats, identifying 46 potential biomarkers, with 16 showing significant changes after treatment.
  • Key pathways related to the efficacy of Epimedium included arachidonic acid and glycerophospholipid metabolism, highlighting how metabolomics can shed light on disease mechanisms and the effects of natural remedies.
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Postmenopausal osteoporosis, the most common type of primary osteoporosis, poses a significant threat to women's health worldwide. However, detailed molecular mechanism and therapeutic strategy for postmenopausal osteoporosis remain insufficient. Increasing evidence suggests that microRNAs contributed to the pathogenesis of osteoporosis and could be considered as potential therapeutic targets.

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Aims: The present study aims to investigate the protective effect and underlying mechanism of Z-Guggulsterone (Z-GS), an active component from myrrh, on glucocorticoid-induced osteoporosis (GIO).

Main Methods: GIO rats were used to simulate osteoporosis in vivo while MC3T3-E1 cells were induced to osteoblast differentiation and treated with dexamethasone to simulate osteoporosis in vitro. The rats and cells were treated with Z-GS according to the protocol.

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  • Osteoporosis poses significant socio-economic challenges, including high medical costs and lifestyle restrictions, while oleanolic acid (OA) is recognized as a natural anti-osteoporosis agent with unclear therapeutic mechanisms.
  • This study investigates OA's anti-osteoporosis effects using a metabolomics approach on rats, focusing on biomarker identification and metabolic pathways linked to OA treatment.
  • Results show OA improves clinical indicators and bone density, influencing key metabolic pathways and potentially restoring balance in carbohydrate and lipid metabolism disrupted by osteoporosis.
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