Publications by authors named "Shui-Xiang Deng"
Article Synopsis
- Monocytes play a key role in systemic inflammation, influenced by HMGB1, which promotes their migration and prevents cell death through various signaling pathways.
- Glycyrrhizin (GL), a component of licorice, reduces the inflammatory effects of HMGB1 by inhibiting these pathways and promoting the apoptosis of monocytes.
- The study found that GL blocked HMGB1-induced monocyte migration and encouraged apoptosis, suggesting it could be a potential treatment to mitigate systemic inflammation by targeting specific signaling pathways.
