Publications by authors named "Shui-Qing He"
Background: To evaluate the efficacy of local-regional radiotherapy (LRRT) in de novo metastatic nasopharyngeal carcinoma (dm NPC) patients receiving chemo-immunotherapy as first-line treatment and select the beneficiaries from LRRT.
Methods And Materials: M1-NPC patients receiving platinum-based chemo-immunotherapy with or without LRRT from four centers were included in this study. The propensity score matching (PSM) analysis was employed to balance the baseline characteristics between the LRRT and non-LRRT groups.
Article Synopsis
- This study focuses on improving the management of patients with de novo metastatic nasopharyngeal carcinoma (NPC) undergoing palliative immuno-chemotherapy (PICT) by predicting individual survival outcomes.
- A nomogram was developed to predict overall survival based on data from 592 patients, identifying key prognostic factors like bone metastasis and the number of metastatic lesions.
- The results indicated that patients with different M1 classifications (M1a vs. M1b) had significantly different survival rates, highlighting the nomogram's clinical usefulness in guiding treatment decisions.*
Objective: Epidemiology studies indicate that green tea polyphenols (GTP) perform a protective effect on cardiovascular diseases, but the underlying mechanisms are complex. The present study aimed to investigate the effect of GTP on high-fat diets (HFD) induced-early vascular aging.
Methods: Six-week young adult Wistar rats were fed with standard chow or HFD in the presence and absence of GTP (200 mg/kg body weight) for 18 weeks.