Research on high-performance, real-time periodic signal detection method based on field-programmable gate arrays (FPGAs).

Long-Time Coherent Integration (LTCI) utilizes digital integration to combine multiple coherent cycles, thereby improving the signal-to-noise ratio (SNR). Our previous work introduced single-bit LTCI, an approach optimized for FPGA implementation, but faced challenges of output saturation at high SNR levels and inherent limitations in SNR gain (SNRG), which are insufficient for certain applications. This paper presents a threshold tracking method that improves the performance of single-bit LTCI in high-SNR scenarios.

The impact of environmental literacy on the health level of rural residents: evidence from the mountainous areas of Sichuan, China.

Introduction: Environmental pollution and health issues are hot topics of discussion in modern society. However, there is a lack of research from the perspective of subjective factors such as environmental protection to study the impact of environmental literacy on health, especially in rural areas.

Methods: First, through field research in the mountainous rural areas of Sichuan Province, 396 data points were collected.

SRC enhanced cisplatin resistance in bladder cancer by reprogramming glycolysis and pentose phosphate pathway.

The development of cisplatin resistance often results in a grim prognosis in advanced or recurrent bladder cancer. However, effective treatment strategies for cisplatin resistance have not been well established. Herein, we found that overactivation of SRC is associated with cisplatin-resistance.

Previous maximal transurethral resection of bladder tumor lead to unfavorable perioperative outcomes following radical cystectomy.

Purpose: To evaluate the impact of maximal transurethral resection of bladder tumor (TURBT) on perioperative outcomes following radical cystectomy (RC).

Methods: This study included 310 patients who underwent RC for the diagnosis of bladder urothelial carcinoma. Of these, 146 patients had a history of maximal TURBT (TURBT group) and 164 did not (non-TURBT group).

[Comparison of clinical efficacy between autologous block bone graft and GBR in horizontal bone augmentation based on Mimics 3D reconstruction].

Purpose: To compare the clinical efficacy of autologous bone block graft and guided bone regeneration (GBR) in horizontal bone augmentation.

Methods: A total of 42 patients were included and divided into two groups. Group A included 20 patients, in whom autologous bone block graft was performed.

Fluorescent poly(tannic acid)-based nanoprobes for selective and sensitive detection of bismuth ions.

Herein, blue luminescent fluorescent poly(tannic acid) nanoparticles (FPTA NPs) were fabricated through chemical degradation of poly(tannic acid) large particles using HO, and the obtained FPTA NPs exhibited excellent water dispersibility, great fluorescence stability, and relatively high quantum yield. More importantly, based on the dynamic quenching and chelation enhanced quenching effect between FPTA NPs and bismuth ions (Bi), a fluorescence method for the rapid identification and detection of Bi was developed. With the increase of Bi, the fluorescence of FPTA NPs could be quenched gradually; the linear range was 0.

Effect of fabrication methods and number of supporting teeth on the surface accuracy and dimensional stability of implant surgical guides.

Statement Of Problem: Implant surgical guides manufactured using different fabrication methods have been commonly used for computer-guided implant placement. However, how fabrication methods and the number of supporting teeth influence accuracy and stability remains uncertain.

Purpose: The purpose of this in vitro study was to evaluate the influence of fabrication methods and number of supporting teeth on the surface accuracy and dimensional stability of implant surgical guides with 3 different 3-dimensional (3D) printers and 1 computer numeric controlled (CNC) milling machine.

Semantic information guided diffusion posterior sampling for remote sensing image fusion.

The task of image fusion for optical images and SAR images is to integrate valuable information from source images. Recently, owing to powerful generation, diffusion models, e.g.

Improved Multi-Size, Multi-Target and 3D Position Detection Network for Flowering Chinese Cabbage Based on YOLOv8.

Accurately detecting the maturity and 3D position of flowering Chinese cabbage ( var. chinensis) in natural environments is vital for autonomous robot harvesting in unstructured farms. The challenge lies in dense planting, small flower buds, similar colors and occlusions.

Failure analysis and design improvement of retrieved plates from revision surgery.

Background: The fracture of bone plate can cause considerable pain for the patient and increase the burden on the public finances. This study aims to explore the failure mechanism of 49 plates retrieved from revision surgery and introduce pure magnesium (Mg) block to improve the biomechanical performance of the plate via decreasing the stiffness and to stimulate the biological response of the plate potentially by the degradation of Mg block.

Methods: The morphological analysis and component analysis of the plates were conducted to determine the fracture reason of the plates combining the clinical data.

Percutaneous endoscopic transforaminal decompression surgery for symptomatic double-level lumbar spinal stenosis with ossification.

This study aimed to explore the short-term effects of percutaneous endoscopic transforaminal decompression (PETD) for the treatment of symptomatic double-level lumbar spinal stenosis (LSS) with ossification. Twenty-eight patients diagnosed with double-level lumbar spinal stenosis who underwent double-level PETD surgery between January 2021 and January 2023 at our institution. General information, such as age, sex, disease duration, hospitalization time, and operation time, was recorded.

Copper dual-doping strategy of porous carbon nanofibers and nickel fluoride nanorods as bi-functional oxygen electrocatalysis for effective zinc-air batteries.

Designing and developing efficient, low-cost bi-functional oxygen electrocatalysts is essential for effective zinc-air batteries. In this study, we propose a copper dual-doping strategy, which involves doping both porous carbon nanofibers (PCNFs) and nickel fluoride nanoparticles with copper alone, successfully preparing copper-doped nickel fluoride (NiF) nanorods and copper nanoparticles co-modified PCNFs (Cu@NiF/Cu-PCNFs) as an efficient bi-functional oxygen electrocatalyst. When copper is doped into the PCNFs in the form of metallic nanoparticles, the doped elemental copper can improve the electronic conductivity of composite materials to accelerate electron conduction.

NF-κB-activated oncogene inhibition strategy for cancer gene therapy.

NF-κB is a promising target for cancer treatment because of its overactivation in almost all cancers but countless NF-κB inhibitors rarely became clinical drugs due to side effects. In contrast to traditional cancer treatments aimed at inhibiting NF-κB activity, this study develop a novel approach termed HOPE, which focuses on activating the exogenous effector gene CRISPR-Cas13a within cancer cells, achieved by utilizing the NF-κB-specific promoter DMP previously constructed, then targets and suppresses the expression of oncogenes TERT, PLK1, KRAS and MYC at mRNA level. We evaluated the antitumour effects of HOPE in various cultured cells and confirmed it could induce obvious the death of cancer cells without affecting normal cells.

Fabrication, sustainability, and key performance indicators of bioelectronics via fiber building blocks.

Bioelectronics provide efficient information exchange between living systems and man-made devices, acting as a vital bridge in merging the domains of biology and technology. Using functional fibers as building blocks, bioelectronics could be hierarchically assembled with vast design possibilities across different scales, enhancing their application-specific biointegration, ergonomics, and sustainability. In this work, the authors review recent developments in bioelectronic fiber elements by reflecting on their fabrication approaches and key performance indicators, including the life cycle sustainability, environmental electromechanical performance, and functional adaptabilities.

The Relationship between Football Participation and Sport Trait Confidence for Adolescents: A Chain-Mediated Effect of Collective Self-Esteem and Self-Esteem.

To investigate the relationship between sports participation and sport trait confidence, 1659 teenagers in primary and secondary schools who regularly play football were asked to complete the Sports Participation Scale, Collective Self-Esteem Scale, Self-Esteem Scale, and Sport Trait Confidence Scale. The results show that (1) the positive prediction of football participation on sport trait confidence is not significant; (2) collective self-esteem and self-esteem play a mediating role between football participation and sport trait confidence; (3) the mediating effect occurs through three pathways. The study provides theoretical guidance and empirical evidence for the lead and intervention of adolescent football participation on sport trait confidence.

The effects of the-optimal-lymph-flow health IT system application on treatment-related high risk lymphedema in breast cancer patients: a randomized controlled trial.

Purpose: To evaluate the application effects of The-Optimal-Lymph-Flow IT System in Chinese patients at high risk of developing breast cancer-related lymphedema.

Methods: A total of 104 breast cancer patients were randomly assigned to either the control group or the intervention group. The intervention group was provided with the The-Optimal-Lymph-Flow program, while the control group received the usual care.

Imperceptible augmentation of living systems with organic bioelectronic fibres.

The functional and sensory augmentation of living structures, such as human skin and plant epidermis, with electronics can be used to create platforms for health management and environmental monitoring. Ideally, such bioelectronic interfaces should not obstruct the inherent sensations and physiological changes of their hosts. The full life cycle of the interfaces should also be designed to minimize their environmental footprint.

A Crosstalk Analysis of high-risk human papillomavirus, microbiota and vaginal metabolome in cervicovaginal microenvironment.

The microbial community has a profound effect on the host microenvironment by altering metabolites. Persistent high-risk human papillomavirus (HRHPV) infection has been implicated as contributors to the initiation and progression of cervical cancer, but the involved mechanisms are unknown. Assessing the metabolic profile of the cervicovaginal microenvironment has the potential to reveal the functional interactions among the host, metabolites and microbes in HRHPV persistence infection and progression to cancer.

Multidisciplinary clinical decision-making of anterior diastema closure.

Anterior diastema is a common esthetic defect in China. The general treatment for a patient with diastemata, including orthodontics and direct and indirect restorations, is a multidisciplinary clinical procedure covering the orthodontics, operative dentistry, general dentistry, and prosthodontics department. Given the diversity of departments and the complex etiology of this defect, decision-making regarding the closing methods and time selection is undefined and unintegrated, which makes the long-term stability of closure unpredictable.

PA-MSHA improves prognosis of patients undergoing radical cystectomy: a retrospective cohort study using inverse probability of treatment weighting.

Objective: To observe the effect of Pseudomonas aeruginosa mannose-sensitive hemagglutinin (PA-MSHA) on the prognosis and the incidence of lymphatic leakage in patients undergoing radical cystectomy (RC).

Method: A total of 129 patients who underwent RC in Lanzhou University Second Hospital from 2013 to 2022 were enrolled in this study. They were divided into 43 patients treated with PA-MSHA and 86 patients in the control group.

Second Harmonic Generation in β-KTeWO: An Acentric Crystal Designed from Centric Phase via Pressure Modulation.

The latent value of nonlinear optical (NLO) crystals applied in solid-state laser equipment necessitates the development of applicable strategies for constructing noncentrosymmetric (NCS) crystals. By modulating the synthetic temperature and pressure to achieve the rearrangement of [TeO] groups, a new NCS tellurium tungstate, β-KTeWO (β-KTW), with a strong second harmonic generation (SHG) response was synthesized based on its centrosymmetric polymorphic phase α-KTeWO (α-KTW). Computational calculation reveals that the large SHG response of β-KTW (15 × KHPO@1064 and 1.

Three dimensionally printed template with an interproximal isolation design guide consecutive closure of multiple diastema with injectable resin composite.

Objective: This article describes a novel 3D-printed template armed with interproximal matrices to isolate interproximal contact areas and guide injectable resin composite for consecutive closure of multiple diastema.

Clinical Considerations: Among several treatment options proposed for diastema closure, direct resin composite is noninvasive and easy to repair. The "composite injection technique" has been introduced to improve time efficiency and reduce technique sensitivity for clinicians.