Synopsis of recent research by authors named "Shuho Semba"
- Shuho Semba's research primarily focuses on the prognostic factors and pathogenesis of various cancers, including colorectal, cervical, esophageal, and gastric cancers, emphasizing the role of tumor microenvironment and associated cellular mechanisms in cancer progression and outcomes.
- Significant findings include the identification of extramural tumor deposits and extracapsular lymph node invasion as poor prognostic indicators in colorectal cancer, and the role of tumor-associated macrophages in the aggressiveness of esophageal squamous cell carcinoma.
- Semba's studies on HPV involvement in cervical lesions, epigenetic factors in Barrett's esophagus, and the expression patterns of specific proteins like WNT5A and SNX2 in cancer development showcase the complex interplay between genetic, epigenetic, and cellular factors in tumor biology.
