Efficacy of Temporary Intentional Leg Shortening and Deformation for Treatment of Massive Bone and Soft Tissue Defects in Three Patients.

Aim: This study describes the intentional deformation and shortening of a limb using external fixation (EF) in three patients with post-traumatic injury tibial defects and to assess the outcomes.

Case Description: Three patients with infected non-unions and massive bone and soft tissue defects who were treated with temporary intentional leg shortening and deformation using a Taylor Spatial Frame (TSF) EF were retrospectively reviewed. The alignment was restored by gradual deformity correction and lengthening after a 2-week interval.

Osteoarthritis of the Fourth and Fifth Tarsometatarsal Joint After Calcaneo-Cuboid Distraction Arthrodesis in Flatfoot Correction.

Lateral column lengthening procedures are typically performed in patients with flatfoot deformity. There have been reports of complications caused by lateral column lengthening. In this study, clinical and radiographic osteoarthritis of the fourth and fifth tarsometatarsal joints were retrospectively assessed as complications after lateral column lengthening.

Patient-reported Outcome and Quality of Life after Treatment with External Fixation: A Questionnaire-based Survey.

Background: This survey aims to assess the satisfaction of patients who have had treatment using external fixation (EF).

Materials And Methods: An original questionnaire and a Short Form 36 (SF-36) were distributed to 121 patients who underwent treatment using EF for deformity correction and lengthening between 2006 and 2016. A multivariate analysis was performed on the factors associated with satisfaction.

Assessment of lateral hindfoot impingement with weightbearing multiplanar imaging in a flatfoot.

Background: Estimation of the lateral hindfoot impingement in the standing position in conventional radiography can be difficult due to superimposition of different bones. Patients with flat feet frequently suffer from pain around the lateral malleolus and sinus tarsi caused by osseous impingement in the lateral hindfoot. Weightbearing multiplanar images (tomosynthesis) yield tomographic images and can be taken while full weightbearing.

Large Osteochondral Defects of the Distal Tibia Plafond After Septic Arthritis of the Ankle Joint Treated by Arthrodiastasis and Iliac Bone Graft: A Case Report.

Bone defects after septic arthritis of the ankle joint result in arthrodesis and severe loss of ankle motion. This must be prevented in young athletes. We report the case of a 17-year-old male patient with large osteochondral defects in the distal tibia plafond after septic arthritis, in whom iliac bone graft and arthrodiastasis were performed to preserve ankle motion.

Comparison of treatment indices associated with the correction and lengthening of deformities along various lower limb frontal plane directions.

Purpose: The Taylor spatial frame (TSF) provides higher precision in the dimensional correction of some lower limb deformities. However, no study to date has compared the osteogenesis outcome of correction and lengthening among various directions in the frontal plane. We examined the relationship between the external fixation index (EFI) and the direction of correction in the frontal plane.

Autologous adipose-derived stem cell transplantation enhances healing of wound with exposed bone in a rat model.

Objectives: Soft tissue wounds with exposed bone often require extended healing times and can be associated with severe complications. We describe the ability of artificial dermis with autogenic adipose-derived stem cells (ADSCs) to promote the healing of wounds with exposed bone in a rat model.

Methods: Adipose tissues harvested from the bilateral inguinal regions of Wistar rats were used as ADSCs.

Adipose-derived stem cell sheets accelerate bone healing in rat femoral defects.

In the present study, we investigated whether both adipose-derived stem cell (ADSC) and osteogenic-induced ADSC sheets could promote bone healing in a rat distal femoral metaphysis bone defect model. A through-hole defect of 1 mm diameter was drilled into each distal femur of 12 week old rats. Forty-five rats were randomly assigned to three groups: (1) control group; (2) ADSC sheet group; or (3) osteogenic-induced ADSC sheet group.

Contribution of methylglyoxal to delayed healing of bone injury in diabetes.

Patients with diabetes are vulnerable to delayed bone fracture healing or pseudoarthrosis. Chronic sustained hyperglycemia, reactive intermediate derivatives of glucose metabolism, such as methylglyoxal (MGO), and advanced glycation end‑products (AGEs) are implicated in diabetic complications. In the present study, it was examined whether MGO is able to cause disturbed bone healing in diabetes.

Simultaneous arthrodiastasis and deformity correction for a patient with ankle osteoarthritis and lower limb deformity: a case report.

We here report a case of a 50-year-old male with ankle osteoarthritis and lower limb deformity, for which simultaneous deformity correction and arthrodiastasis were performed. The patient initially experienced an open fracture on the left tibia at 19 years, but it was malunited. The Japanese Society for Surgery score of the foot for the left ankle was 53 points.