[Relationship between serum calcium level and PTH concentration proved with sevelamer hydrochloride].

About a dialysis patient's calcium-phosphate (Ca.P) metabolism, in general good control is obtained by use of sevelamer hydrochloride. As for this, what is significantly depended on not only lower P concentration but also lower Ca concentration by the change to sevelamer hydrochloride from calcium carbonate.

[Treatment with phosphate binder (sevelamer hydrochloride, calcium carbonate) based on PTH].

When sevelamer hydrochloride is used as a phosphate binder instead of the more common calcium carbonate, the PTH rises. This has been observed in many cases and makes it more difficult for practical use. However, considering the calcium load, the excessive dosing of calcium carbonate must be avoided.