Publications by authors named "Shuhei Chigasaki"
Biochemistry
November 2017
Article Synopsis
- The study focuses on how tafazzin remodels acyl chain compositions of cardiolipin (CL) in mitochondria, highlighting its role in maintaining mitochondrial function.
- Researchers examined the effects of different acyl chain compositions of phosphatidylcholine (PC) on tafazzin's transacylation ability, particularly comparing dipalmitoleoyl (16:1) PC with dipalmitoyl (16:0) PC.
- Results showed that tafazzin is selective about the molecular configuration of acyl chains, indicating a need to reconsider the thermodynamic remodeling hypothesis that suggests no acyl selectivity.
