Publications by authors named "Shuhao Li"

Sertoli cells play an important role in the process of spermatogenesis by providing energy for spermatogenic cells and themselves through glycolysis and fatty acid oxidation. Abnormalities in spermatogenesis are closely related to disruptions of glucose and lipid metabolism in Sertoli cells. The metabolic environment of Sertoli cells is hypoxic, with glycolysis and fatty acid β-oxidation being the primary metabolic pathways.

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The pervasive utilization of plastic products has led to a significant escalation in plastic waste accumulation. Concurrently, the implications of emerging pollutants such as microplastics (MPs) and nanoplastics (NPs) on human health are increasingly being acknowledged. Recent research has demonstrated that MPs/NPs may contribute to the onset of human aging and age-related diseases.

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Modulating the intrinsic activity of heterogeneous catalysts at the atomic level is an effective strategy to improve the low-temperature CO-SCR (selective catalytic reduction) reaction activity and N selectivity, but it remains challenging by the experiment. In this paper, a single-atom-loaded surface generation strategy is developed to construct single-atom catalysts by density functional theory analysis, which will effectively reduce the reaction energy barriers in CO-SCR reaction. Specifically, the reaction of NO reduction by CO before and after Ni adsorption was thoroughly investigated and the reactivity was evaluated by using the CeO (1 1 1) surface as a carrier, with the application of density functional theory, electronic structure analysis, and transition state theory.

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Background: Ureteral stents, including internal stents and stentless techniques, are commonly employed in urological procedures such as urinary stone management and deformity correction. However, their use in radical cystectomy for bladder cancer remains relatively limited. This study aimed to compare the efficacy of internal stent, external stent, and no-stent treatments for ureteroileal anastomosis in laparoscopic radical cystectomy (LRC) combined with ileal orthotopic neobladder (IONB).

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Background: Post-biopsy acute urinary retention (AUR) is still a common complication, often leading to extended hospital stays and greater patient discomfort. This study aimed to develop and validate a nomogram for the early identification of AUR after transrectal prostate biopsy (TRPB).

Methods: We collected data on patients who underwent TRPB at The Third Affiliated Hospital of Sun Yat-sen University between January 2019 and November 2023, including all characteristics and prostate morphological parameters.

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Purpose: To investigate the left ventricular (LV) trabecular complexity and evaluate its relationship with LV cardiac function and especially myocardial strain in patients with hypertrophic cardiomyopathy (HCM).

Materials And Methods: A total of 100 patients were retrospectively recruited in the study, including 50 obstructive hypertrophic cardiomyopathy (HOCM) and 50 nonobstructive HCM (NOHCM). Fifty age-matched and sex-matched healthy participants were also enrolled.

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Background: Early prediction of left ventricular reverse remodeling (LVRR) can guide the subsequent treatment in dilated cardiomyopathy (DCM) patients. We aimed to investigate the value of left atrium (LA) strain for predicting LVRR in DCM patients.

Methods: Clinical and imaging data of DCM patients were gather between January 2018 and January 2023.

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Purpose: We conducted a more comprehensive systematic review and meta-analysis to evaluate the effectiveness of auricular acupuncture (AA) in perioperative pain management.

Methods: Randomized controlled trials (RCTs) findings were retrieved from the Embase, Cochrane Central Register of Controlled Trials, PubMed, Web of Science, Chinese Biomedical Literature Database, Wanfang, VIP, and China National Knowledge Infrastructure databases from their inception to March 2024 using the search terms "pain", "auriculotherapy", and "randomized controlled trial". The experimental group was treated with AA alone or in combination with analgesic drugs, whereas the control group was treated with sham auricular acupuncture, placebo, conventional treatment, or no treatment.

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Introduction: Postoperative ileus (POI) is an inevitable complication after abdominal surgery, often hindering recovery and prolonging hospital stay. Despite the increasing use of electroacupuncture (EA) as an alternative treatment for gastrointestinal dysfunction, its effectiveness for POI is still controversial. This study aims to verify the efficacy and safety of EA in alleviating POI.

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Article Synopsis
  • The study investigates how to effectively assess muscle involvement in children with Becker muscular dystrophy using quantitative magnetic resonance imaging (qMRI).
  • It compares different qMRI parameters (fat fraction, T1, and T2) between affected children and healthy controls, finding that fat fraction in the gluteus maximus is the most effective marker.
  • The results suggest that measuring fat fraction can predict functional decline in these children, making it a valuable biomarker for monitoring disease progression.
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Pyroptosis, driven by the N-terminal domain of gasdermin proteins (GSDM), promotes antitumor immunity by attracting lymphocytes to the tumor microenvironment (TME). However, current pyroptosis-inducing therapies like drug injections and phototherapy are limited to localized treatments, making them unsuitable for widespread or microscopic metastatic lesions. This study engineered oncolytic M1 viruses (rM1-mGSDME_FL and rM1-mGSDME_NT) to selectively deliver GSDME to tumor cells.

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Information storage and anti-counterfeiting are two very important applications of photochromic materials. Photochromic materials with both information storage and anti-counterfeiting should meet the requirements including fast coloration, good stability and reversibility, low storage cost, and practical application value. Herein, a novel viologen-based coordination polymer, Cd[(pbpy)(HBTC)Cl]·2HO (1) (pbpy = 1,1'-[1,4-phenylenebis-(methylene)]bis(4,4'-bipyridinium); HBTC = 1,3,5-benzenetricarboxylic acid), has been constructed.

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Article Synopsis
  • Postoperative ileus (POI) is a significant complication after abdominal surgery, leading to extended recovery times, higher costs, and a challenge to public health.
  • Recent research highlights the role of beta adrenergic signaling in POI and identifies various triggers, but the current global research landscape remains unclear.
  • A bibliometric analysis of publications from 2011 to 2023 reveals an increase in POI research, with China and the USA leading in contributions, and suggests the need for multidisciplinary collaboration to advance understanding in this area.
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Altered metabolism is a hallmark of cancer, and reprogramming of energy metabolism, known as the "Warburg effect", has long been associated with cancer. Cancer cells use the process of glycolysis to quickly manufacture energy from glucose, pyruvic acid, and lactate, which in turn accelerates the growth of cancer and glycolysis becomes a key target for anti-cancer therapies. Recent groundbreaking discoveries regarding long noncoding RNAs (lncRNAs) have opened a new chapter in the mechanism of cancer occurrence.

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Article Synopsis
  • Mitochondrial dysfunction during aging contributes to age-related diseases, as damaged mitochondria lead to inflammation and oxidative stress.
  • Mitophagy is a selective process that removes defective mitochondria, helping to maintain cellular health and stability.
  • The paper explores the mechanisms of mitophagy, its connection to aging and stress, and suggests directions for future research on the topic.
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Background: Psoriasis is a chronic systemic disorder with ocular involvement.

Objectives: To evaluate the risk of glaucoma among patients with psoriasis.

Methods: Participants in this cohort study were selected based on Chang Gung Research Database from 1 January 2003 to 31 December 2012.

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Takotsubo syndrome (TTS), commonly referred to as "broken heart syndrome," is a distinctive form of acute and reversible heart failure that primarily affects young to middle-aged individuals, particularly women. While emotional or physical stressors often trigger TTS, rare cases have been linked to interventional procedures for congenital heart disease (CHD). Despite its recognition, the exact causes of TTS remain elusive.

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  • Cytokinins (CKs) are plant hormones that play a key role in growth and development, with specific genes involved in their degradation and biosynthesis that help maintain CK levels.
  • The study focuses on analyzing the roles of two specific genes in cucumber, investigating their protein properties, expression patterns in various tissues, and responses to environmental stresses like low light, salt, and drought.
  • The research identified eight genes related to each function, found that these genes are highly expressed in roots and male flowers, and aims to provide insights for further understanding of their roles in cucumber growth and stress responses.
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Introduction: The metro has emerged as a major mode of transportation. A significant number of commuters and staff in the metro system are exposed to air pollutants because of its shielded environment, and substantial health damage requires quantitative assessment. Previous studies have focused on comparing the health impacts among different transportation modes, overlooking the specific population characteristics and pollutant distribution in metro systems.

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Background: Hypertrophic cardiomyopathy (HCM) is a common genetic cardiac disorder characterized by the hypertrophy of a segment of the myocardium. Cardiac magnetic resonance (CMR) has been widely used in the assessment of HCM. However, no bibliometric assessment has been conducted on the progress of research in this field.

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Background: Virtual monoenergetic images (VMIs) at a low energy level can improve image quality when the amount of iodinated contrast media (CM) is reduced. The purpose was to evaluate the feasibility of using an extremely low CM volume and injection rate in cerebral computed tomography angiography (CTA) on a dual-layer spectral detector computed tomography (CT).

Methods: Patients who were clinically suspected of intracranial aneurysm or cerebrovascular diseases were included in our study (from June to November 2022).

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Article Synopsis
  • * Researchers identified six genes related to proline transport through genome sequencing, revealing three evolutionary branches and common structural features among them.
  • * Analysis of these genes suggests their function in heat stress response, where expression patterns indicate significant activity in petioles and under high temperatures, with further testing showing enhanced proline transport in genetically modified Arabidopsis plants.
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Our experiments explored the effects of far-red (FR) light on cucumber (Cucumis sativus L. 'Zhongnong No. 26') seedling growth.

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