Fisetin-induced cell death in human ovarian cancer cell lines via zbp1-mediated necroptosis.

Background: Among reproductive cancers, ovarian cancer leads to the highest female mortality rate. Fisetin, a natural flavonoid, exerts pharmacological effects, inhibiting cancer growth with various origins. Although multiple mechanisms are involved in regulating cell death, it is still unclear whether and how fisetin exhibits anticancer effects on ovarian cancer.

Breast milk and infant iodine status during the first 12 weeks of lactation in Tianjin City, China.

Background And Objectives: The present study investigated the iodine status of breast milk and breast-fed infants during the first 12 weeks postpartum in Tianjin, China.

Methods And Study Design: A total of 175 pregnant women were recruited before delivery. Their breastmilk and 24-h urine samples were collected at 4, 8, and 12 weeks postpartum; spot urine samples were simultaneously collected from their infants.