Publications by authors named "Shuguang Zhen"

Article Synopsis
  • Fournier's Gangrene is a serious infectious disease that can lead to high mortality rates, and this study analyzes patient characteristics and factors related to mortality.
  • The research involved 46 patients hospitalized for Fournier's Gangrene at a specific hospital over a span of more than a decade and used various clinical data and scoring systems to evaluate health outcomes.
  • Results showed that the majority of patients were male, with a median age of 61, and most survived three months post-treatment, although a few patients did not survive due to severe illness.
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Objective:  There is limited data on the pathogenic microorganisms associated with anorectal abscesses. The purpose of this study was to retrospectively analyze the types and quantities of pathogenic microorganisms in the pus cultures of patients with anorectal abscesses and to explore the correlation between pathogenic microorganisms and types of anorectal abscesses.

Methods:  A retrospective analysis was conducted on the microbiological data of 517 inpatient surgical patients with anorectal abscesses treated at a single center from January 2017 to December 2021.

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Background And Objectives: This study aimed to investigate independent risk factors for intra-abdominal infection and to construct a nomogram to identify colorectal patients at a high risk of intra-abdominal infection.

Methods And Study Design: Clinical data of patients undergoing radical resection of colorectal cancer from January 2019 to December 2021 were retrospectively included in this study. Patients were divided into two groups according to postoperative intra-abdominal infection.

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Ulcerative colitis (UC) is a chronic inflammatory colorectal disease characterized by excessive mucosal immune response activation and dysfunction of autophagy in intestinal epithelial cells. Traditional herbal preparations, including the Huangkui lianchang decoction (HLD), are effective in UC clinical treatment in East Asia, but the underlying mechanism is unclear. This study evaluated the therapeutic effects and associated molecular mechanisms of HLD in UC and .

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Background: It is important but difficult to treat complex fistula-in-ano due to the high recurrent rate and following incontinence. Ligation of the intersphincteric fistula tract (LIFT), a novel surgical procedure with the advantage of avoiding anal incontinence, has a variable success rate of 57-94.4 %.

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Traditional Chinese medicine was reported to have good effects in treating functional constipation. This work attempted to prove the effects of aqueous extracts of (AEHC) on STC treatment and to determine the possible mechanisms by a loperamide-induced slow transit constipation (STC) model. HPLC was performed for identification and confirmation of the bioactive components in the AEHC.

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