Publications by authors named "Shugo Kazama"
Article Synopsis
- - Desmin expression was studied in the myometrium and cervix of peripartum rats, showing lower mRNA levels in the cervix compared to ovariectomized rats, but increased protein presence in the myometrium at key developmental days (DP17, 21, and day of birth).
- - Western blot analysis revealed that desmin protein levels significantly rose in both the myometrium (4- to 6-fold increase) and cervix (10-fold increase at DP21) but dropped sharply after birth, pointing to a discrepancy between mRNA and protein levels, especially in the cervix.
- - The study suggested that estradiol regulates desmin levels, with S-nitrosylated
The involvement of nitric oxide (NO) signaling in apoptosis was examined in the placental bed of mid-to-late pregnant rats. Pregnant rats were treated with l-NAME, a nitric oxide synthase inhibitor, by subcutaneous infusion for 48 hours before the examination at day 13.5, 17.
View Article and Find Full Text PDFThe inhibition of neural crest cell (NCC) migration has been considered as a possible pathogenic mechanism underlying chemical developmental toxicity. In this study, we examined the effects of 13 developmentally toxic chemicals on the migration of rat cephalic NCCs (cNCCs) by using a simple in vitro assay. cNCCs were cultured for 48 h as emigrants from rhombencephalic neural tubes explanted from rat embryos at day 10.
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