Fast, high-quality, and unshielded 0.2 T low-field mobile MRI using minimal hardware resources.

Objective: To propose a deep learning-based low-field mobile MRI strategy for fast, high-quality, unshielded imaging using minimal hardware resources.

Methods: Firstly, we analyze the correlation of EMI signals between the sensing coil and the MRI coil to preliminarily verify the feasibility of active EMI shielding using a single sensing coil. Then, a powerful deep learning EMI elimination model is proposed, which can accurately predict the EMI components in the MRI coil signals using EMI signals from at least one sensing coil.

Multi-target field control for matrix gradient coils.

Objective: Conventional single-target field control for matrix gradient coils will add control complexity in MRI spatial encoding, such as designing specialized fields and sequences. This complexity can be reduced by multi-target field control, which is realized by optimizing the coil structure according to target fields.

Methods: Based on the principle of multi-target field control, the X, Y and Z gradient fields can be set as target fields, and all coil elements can then be divided into three groups to generate these fields.

Family aggregation and prevalence of other autoimmune diseases in SAPHO syndrome.

Objective: SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis) syndrome is a heterogeneous disease that clinically manifests as chronic inflammatory osteoarticular and dermatological lesions. Few reports have described familial clustering of SAPHO syndrome cases. This research aimed to illustrate the family aggregation of SAPHO syndrome and investigate the prevalence of autoimmune disorders among SAPHO syndrome patients and first-degree relatives in a large cohort.

Optimization design of a permanent magnet used for a low field (0.2 T) movable MRI system.

Objective: To design a lightweight permanent magnet for a lowfield movable head imaging MRI system.

Materials And Methods: To reduce the weight of the magnet, the pole pieces, anti-eddy current plates, and shimming rings were removed, and the distance between the two vertical yokes was shortened as much as possible. To compensate for the magnetic field deformation caused by the shortened distance between two vertical iron yokes, two side magnetic poles were added to the vertical yokes.

A Case of Neutrophilic Dermatoses-Sweet's Syndrome Coexisting with SAPHO Syndrome.

SAPHO (synovitis, acne, pustulosis, hyperostosis, osteitis) syndrome is a rare disease characterized by osteoarticular and cutaneous manifestations. SAPHO syndrome mostly involves the skin, mainly presented as palmoplantar pustulosis and severe acne. Sweet's syndrome (SS) is a neutrophilic dermatosis of unknown cause, which may be caused by autoinflammation.

Synovitis, acne, pustulosis, hyperostosis, osteitis syndrome with invisible organizing pneumonia: A case report.

We report the case of a 59-year-old female patient, presenting with pustular rash on both hands and pain in the lumbosacral part and left lower limb. A magnetic resonance imaging examination of the left leg was undertaken and the result showed that a malignant lesion with bone destruction of the left femoral shaft could not be excluded. Subsequently, bone tumor was excluded by pathological examination.

Using imaging methods to assess severe calcinosis in juvenile dermatomyositis: A case report.

Calcinosis and lipodystrophy are severe complications of juvenile dermatomyositis (JDM). Up to 20% of patients have calcinosis, and the onset of calcinosis usually occurs 1 to 3 years after that of the illness. We report a case of JDM with severe complications of calcinosis and lipodystrophy, and we assess calcinosis using a variety of imaging methods.

Work productivity and activity in patients with SAPHO syndrome: a cross-sectional observational study.

Background: Our understanding of work productivity impairment among patients with synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is limited. The purpose of this study was to provide an overview of work productivity loss in SAPHO syndrome patients through the use of the work productivity and activity impairment (WPAI) questionnaire, as well as to investigate the relationship between the WPAI and other disease-related indicators.

Methods: Patients for this cross-sectional study were recruited from Peking Union Medical College Hospital (Beijing, China).

Coincidence of pachydermoperiostosis and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome, a causal or casual association?

Pachydermoperiostosis (PDP) is a rare disorder characterized by skin thickening, acropachia, and periostosis. Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome is also an orphan disease featured by different dermatological and osteoarthritic manifestations. Herein, we report the first case of an adolescent male diagnosed with both PDP and SAPHO syndrome, presenting with digital clubbing, polyarthralgia, ostealgia, pachydermia and acne on his face, chest and back.

China rheumatoid arthritis registry of patients with Chinese medicine (CERTAIN): Rationale, design, and baseline characteristics of the first 11,764 enrollees.

Background: Chinese medicine (CM) has become a popular interventional treatment for rheumatoid arthritis (RA). However, limited knowledge about general characteristics and long-term clinical outcomes hampers the development of CM for RA.

Purpose: The main objectives of the China Rheumatoid Arthritis Registry of Patients with Chinese Medicine (CERTAIN) were to describe the population of RA patients receiving CM treatment in multiple centers in China using different variables and compare these findings with internationally reported data.

Analysis on matrix gradient coil modeling.

Objective: The current distribution of the matrix gradient coil can be optimized via matrix gradient coil modeling to reduce the Lorentz force on individual coil elements. Two different modeling approaches are adopted, and their respective characteristics are summarized.

Methods: The magnetic field at each coil element is calculated.

Analysis of coil element distribution and dimension for matrix gradient coils.

Objective: The goal of this work is to analyze the influence of the distributions and dimensions of the coil elements and to present a method for improving the performance of the matrix gradient coil.

Methods: Three typical models (five structures in total) are presented, and a double-layer biplanar matrix gradient coil is used to install coil elements. Two metrics, namely, the role of coil elements and mutual inductance between coil elements, are proposed to assess the performance of coil systems.

Efficacy and safety of Tibetan medicine Qingpeng ointment for acute gouty arthritis: protocol for a multi-center, randomized, double-blind, placebo-controlled trial.

Background: Acute gouty arthritis (AGA) is an inflammatory arthritis clinically characterized by severe pain, swelling, and restricted movement of joints, which may cause physical disability and decrease quality of life. The use of recommended first-line treatment agents for AGA may be limited by adverse events. There has been a traditional use of alternative therapies for AGA.

Near-Null Magnetic Field Suppresses Fruit Growth in Arabidopsis.

We previously found that a near-null magnetic field affected reproductive growth in Arabidopsis under white light. To test whether the effect of a near-null magnetic field on fruit growth of Arabidopsis is related to cryptochrome, we grew wild-type Arabidopsis and cryptochrome double mutant, cry1/cry2, in a near-null magnetic field under blue light. We found that fruit growth of wild-type Arabidopsis instead of the cry1/cry2 mutant was suppressed by the near-null magnetic field.

Suppression of Arabidopsis flowering by near-null magnetic field is mediated by auxin.

We previously found that flowering of Arabidopsis was suppressed by near-null magnetic field, which was related to cryptochrome. Auxin plays an important role in Arabidopsis flowering. To test whether auxin is involved in the suppression of Arabidopsis flowering by near-null magnetic field, we detected auxin level and expressions of auxin transport and signaling genes in wild-type Arabidopsis plants and cryptochrome double mutant, cry1/cry2, grown in near-null magnetic field.

Gibberellins are involved in effect of near-null magnetic field on Arabidopsis flowering.

We previously found that flowering of Arabidopsis was suppressed by near-null magnetic field, which was related to the modification of cryptochrome. To disclose the physiological mechanism of this effect, we detected gibberellin (GA) levels and expressions of GA biosynthetic and signaling genes in wild type Arabidopsis plants and cryptochrome double mutant, cry1/cry2, grown in near-null magnetic field. We found that levels of GA , GA , GA , and GA in wild type plants in near-null magnetic field were significantly decreased compared with local geomagnetic field controls.

Suppression of Arabidopsis flowering by near-null magnetic field is affected by light.

We previously reported that a near-null magnetic field suppressed Arabidopsis flowering in white light, which might be related to the function modification of cryptochrome (CRY). To further demonstrate that the effect of near-null magnetic field on Arabidopsis flowering is associated with CRY, Arabidopsis wild type and CRY mutant plants were grown in the near-null magnetic field under blue or red light with different light cycle and photosynthetic photon flux density. We found that Arabidopsis flowering was significantly suppressed by near-null magnetic field in blue light with lower intensity (10 µmol/m(2) /s) and shorter cycle (12 h period: 6 h light/6 h dark).

Removal of the local geomagnetic field affects reproductive growth in Arabidopsis.

The influence of the geomagnetic field-removed environment on Arabidopsis growth was investigated by cultivation of the plants in a near-null magnetic field and local geomagnetic field (45 µT) for the whole growth period under laboratory conditions. The biomass accumulation of plants in the near-null magnetic field was significantly suppressed at the time when plants were switching from vegetative growth to reproductive growth compared with that of plants grown in the local geomagnetic field, which was caused by a delay in the flowering of plants in the near-null magnetic field. At the early or later growth stage, no significant difference was shown in the biomass accumulation between the plants in the near-null magnetic field and local geomagnetic field.

Construction and operation of a microrobot based on magnetotactic bacteria in a microfluidic chip.

Magnetotactic bacteria (MTB) are capable of swimming along magnetic field lines. This unique feature renders them suitable in the development of magnetic-guided, auto-propelled microrobots to serve in target molecule separation and detection, drug delivery, or target cell screening in a microfluidic chip. The biotechnology to couple these bacteria with functional loads to form microrobots is the critical point in its application.