Eicosapentaenoic acid and Arachidonic acid Protection Against Left Ventricle Pathology: the Multi-Ethnic Study of Atherosclerosis.

Background: We have shown that ω3 polyunsaturated fatty acids (PUFAs) reduce risk for heart failure, regardless of ejection fraction status. Ventricular remodeling and reduced ventricular performance precede overt hear failure, however there is little insight into how PUFAs contribute to maladaptive signaling over time. PUFAs are agonists for regulatory activity at g-protein coupled receptors such as Ffar4, and downstream as substrates for monooxygenases (e.

Prospective study of sleep duration, snoring and risk of heart failure.

Objective: To investigate whether nighttime sleep duration and snoring status were associated with incident heart failure (HF).

Methods: A prospective study was conducted based on Kailuan cohort including 93 613 adults free of pre-existing cardiovascular diseases. Sleep duration and snoring status were assessed by self-reported questionnaire.

[Current status and research advances of high-temperature hazards in rice].

High temperature stress occurs frequently in rice due to global warming. High-temperature hazard during the booting-flowering and grain-filling stages is one of the major factors limiting rice yield and quality. Here, we summarized the occurrence characteristics (identification, classification, region, and time) of high-temperature hazards, and the effects of high temperature on rice growth and development, including physiology, grain yield, and grain quality.

Free fatty acid receptor 4 responds to endogenous fatty acids to protect the heart from pressure overload.

Aims: Free fatty acid receptor 4 (Ffar4) is a G-protein-coupled receptor for endogenous medium-/long-chain fatty acids that attenuates metabolic disease and inflammation. However, the function of Ffar4 in the heart is unclear. Given its putative beneficial role, we hypothesized that Ffar4 would protect the heart from pathologic stress.

Predicting Risk for Incident Heart Failure With Omega-3 Fatty Acids: From MESA.

Objectives: The aim of this study was to determine if plasma eicosapentaenoic acid (EPA) abundance (%EPA) is associated with reduced hazard for primary heart failure (HF) events in the MESA (Multi-Ethnic Study of Atherosclerosis) trial.

Background: Clinical trials suggest that omega-3 polyunsaturated fatty acids (ω3 PUFAs) prevent sudden death in coronary heart disease and HF, but this is controversial. In mice, the authors demonstrated that the ω3 PUFA EPA prevents contractile dysfunction and fibrosis in an HF model, but whether this extends to humans is unclear.

Association of Trajectory of Cardiovascular Health Score and Incident Cardiovascular Disease.

Importance: The American Heart Association 2020 Strategic Impact Goals target an improvement in overall cardiovascular health, as assessed by 7 health metrics (smoking, body weight, physical activity, diet, plasma glucose level, plasma cholesterol level, and blood pressure).

Objective: To examine whether trajectories of overall cardiovascular health over time, as assessed by the cardiovascular health score (CHS) in 2006, 2008, and 2010, are associated with subsequent risk of CVD.

Design, Setting, And Participants: The Kailuan study is a prospective, population-based study that began in 2006.

Sedentary time, metabolic abnormalities, and all-cause mortality after myocardial infarction: A mediation analysis.

Background: Sedentary time was associated with myocardial infarction (MI) and metabolic diseases in previous studies.

Purpose: To investigate whether sedentary time measured before disease onset was associated with all-cause mortality among MI survivors and whether the sedentary time-mortality association was mediated by physical activity status and metabolic phenotypes.

Methods: In this prospective community-based cohort including 101,510 Chinese adults, we used sedentary time, evaluated at 2006 (baseline), to predict further all-cause mortality among individuals who then developed new onset MI from 2006 to December 2013 ( n = 989).

Tea Consumption and Longitudinal Change in High-Density Lipoprotein Cholesterol Concentration in Chinese Adults.

Background: The relation between tea consumption and age-related changes in high-density lipoprotein cholesterol (HDL-C) concentrations remains unclear, and longitudinal human data are limited. The aim of current study was to examine the relation between tea intake and longitudinal change in HDL-C concentrations.

Methods And Results: Baseline (2006) tea consumption was assessed via a questionnaire, and plasma HDL-C concentrations were measured in 2006, 2008, 2010, and 2012 among 80 182 individuals (49±12 years of age) who did not have cardiovascular diseases or cancer, or did not use cholesterol-lowering agents both at baseline (2006) and during the follow-up period (2006-2012).

Smell and Taste Dysfunction Is Associated with Higher Serum Total Cholesterol Concentrations in Chinese Adults.

Several lipid-related hormones and peptides, such as glucagon-like peptide-1 and leptin, are involved in the regulation of taste and smell function. However, to our knowledge, it remains unknown whether these chemosensory functions are associated with lipid profiles. We examined the cross-sectional association between taste and smell dysfunction and blood cholesterol concentrations.

Longitudinal study of alcohol consumption and HDL concentrations: a community-based study.

In cross-sectional studies and short-term clinical trials, it has been suggested that there is a positive dose-response relation between alcohol consumption and HDL concentrations. However, prospective data have been limited. We sought to determine the association between total alcohol intake, the type of alcohol-containing beverage, and the 6-y (2006-2012) longitudinal change in HDL-cholesterol concentrations in a community-based cohort.

ω3-Polyunsaturated fatty acids for heart failure: Effects of dose on efficacy and novel signaling through free fatty acid receptor 4.

Heart failure (HF) affects 5.7 million in the U.S.

[Role of vaccination in chronic disease prevention and control].

Chronic non-communicable disease is a major public health problem affecting the health of residents in china. Evidence shows that, in addition to four major risk factors, i.e.

[Comparison of HbA1c and oral glucose tolerance test for diagnosing diabetes].

Objective: To compare the performance of glycated hemoglobin (HbA1c) and oral glucose tolerance test (OGTT) in diagnosing diabetes and pre-diabetes in the general population.

Methods: A total of 1416 subjects from Nanchang, Jiangxi Province and Wuhan, Hubei Province who have participated the 2010 Chinese Nutrition and Health Survey were studied and their HbA1c were measured. The glycemic levels and distribution of the subjects diagnosed with diabetes and pre-diabetes by OGTT and HbA1c were compared.