Magnitude of Anemia and Hematological Predictors among Children under 12 Years in Odisha, India.

Background. Anemia is a wide spread public health problem in India which affects children. The present study evaluates the prevalence of anemia and status of various hematological parameters among children of Khurda district, Odisha.

Fat-soluble antioxidant vitamins, iron overload and chronic malnutrition in β-thalassemia major.

Objective: To assess the antioxidant vitamins A (retinol) and E (α-tocopherol) levels, iron status and growth retardation in children with β-thalassemia major in Odisha, an eastern state of India.

Methods: Forty three children aged 1-15 y diagnosed with β-thalassemia major (28 males and 15 females) and 42 age-matched healthy controls (22 males and 20 females) were studied. β-thalassemia was detected by using Bio-rad variant assay.

Vitamin A status and hematological values in sickle cell disorder cases.

Background: Sickle cell anemia (SCA), which is an inherited blood disorder characterized primarily by chronic anemia and oxidative stress plays a major role in pathophysiology.

Objective: This study aims to evaluate vitamin A (serum retinol) status and hematological parameters in children with homozygous and heterozygous sickle cell disorders and compared with age- and sex-matched healthy controls.

Materials And Methods: A sample of 80 referred cases (37 sickle cell disorders and 43 normal cases) aged 2-40 years were included in the study.