AURKA inhibitor-induced PD-L1 upregulation impairs antitumor immune responses.

Introduction: Tumor immunotherapy targeting PD-L1 has emerged as one of the powerful tools for tumor therapy. Numerous studies indicate that tumor-targeted drugs critically have an influence on the interaction between the immune system and tumors by changing the expression of PD-L1, which is beneficial for immunotherapy. Our study provided novel evidence for improving the drug regimen in tumor targeted therapy and immunotherapy.

Direct Evidence Demonstrates that f. sp. Infects Susceptible Barberry to Complete Sexual Cycle in Autumn.

Wheat stripe rust is an airborne and destructive disease caused by a heteroecious rust fungus f. sp. ().

Molecular Characterization of Novel Totivirus-Like Double-Stranded RNAs from f. sp. , the Causal Agent of Wheat Stripe Rust.

Characterization of newly isolated mycoviruses may contribute to understanding of the evolution and diversity of viruses. Here, a deep sequencing approach was used to analyze the double-stranded RNA (dsRNA) mycoviruses isolated from field-collected samples in China. Database searches showed the presence of at least four totivirus-like sequences, termed virus 1 to 4 (PsV1 to 4).

Identification of a Novel Strain Able to Hyperparasitize f. sp. , the Causal Agent of Wheat Stripe Rust.

The obligate bitrophic fungus f. sp. () causes stripe (yellow) rust on wheat worldwide.

Screening for simple sequence repeat markers in Puccinia striiformis tritici based on genomic sequence.

Puccinia striiformis f. sp. tritici (Pst) is the obligate biotrophic fungus responsible for stripe rust wheat.