Publications by authors named "Shubo Guo"

Article Synopsis
  • Sinomenine hydrochloride (SH) has limited use in treating rheumatoid arthritis due to gastrointestinal side effects, particularly in the elderly who experience varying gastric emptying times.* -
  • To improve drug efficacy and minimize side effects, new sustained-release pellets were developed, combining regular and enteric-coated formulations optimized through careful design.* -
  • The study achieved high efficiency in drug encapsulation and stable release profiles, showing potential for better SH formulations and providing valuable insights for future research.*
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In this study, near-infrared (NIR) spectroscopy and high-performance liquid chromatography (HPLC) combined with chemometrics tools were applied for quick discrimination and quantitative analysis of different varieties and origins of samples. Based on NIR data, orthogonal partial least squares discriminant analysis (OPLS-DA) and K-nearest neighbor (KNN) models achieved greater than 90% discriminant accuracy of the three species and two origins of . Moreover, the contents of three active ingredients (atractyloxin, atractylone, and β-eudesmol) in were simultaneously determined by HPLC.

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The mechanical properties of various Ti-6Al-4V alloys are influenced by their respective microstructures. This study generated an ultrafine-grain (UFG) Ti-6Al-4V alloy featuring bimodal grain distribution characteristics achieved through initial heat treatment, multi-axial forging (MF), and annealing. The study also extensively examined the evolution process of the alloy's microstructure.

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Introduction: Chrysanthemi Flos (CF) is widely used as a natural medicine or tea. Due to its diverse cultivation regions, CF exhibits varying quality. Therefore, the quality and swiftness in evaluation holds paramount significance for CF.

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