Quantification of bone changes in a collagen-induced arthritis mouse model by reconstructed three dimensional micro-CT.

Background: Inflammatory arthritis is a chronic disease, resulting in synovitis and subchondral and bone area destruction, which can severely affect a patient's quality of life. The most common form of inflammatory arthritis is rheumatoid arthritis (RA) in which many of the disease mechanisms are not well understood. The collagen-induced arthritis (CIA) mouse model is similar to RA as it exhibits joint space narrowing and bone erosion as well as involves inflammatory factors and cellular players that have been implicated in RA pathogenesis.

Laparoscopic resection of small bowel sarcoma.

A 45-year-old female who presented with nausea, vomiting, abdominal pain, and anemia was found to have an 8 × 5 × 5 cm ileal tumor on CT imaging. Laparoscopic evaluation and small bowel resection was performed with clear margins with a diagnosis of low-grade leiomyosarcoma. Small intestine leiomyosarcoma is very rare, and there are no prior reports of laparoscopic resection.