Publications by authors named "Shubhankar Mehrotra"
Effects of i-PRF, A-PRF+, and EMD on Osteogenic Potential of Osteoblasts on Titanium.
Clin Implant Dent Relat Res
October 2024
Objective: The study evaluates three biologically active substances with known bone-inductive potential on previously decontaminated titanium (Ti) discs.
Material And Methods: Rough and smooth Ti surfaces were contaminated with a multispecies biofilm and cleaned with a chitosan brush. Discs were treated either with injectable-platelet-rich fibrin (i-PRF), advanced platelet-rich fibrin (A-PRF+), or enamel matrix derivatives (EMDs) before osteoblast seeding.
Article Synopsis
- Socket preservation is a surgical technique used to maintain alveolar bone dimensions after tooth extraction, with recent studies exploring the use of extracted dentine as an autograft material.
- A systematic review protocol is being developed to assess the effectiveness of dentine compared to traditional bone grafts, focusing on randomized and non-randomized studies that utilize this material for socket preservation.
- The findings will help inform dental clinicians and patients about using dentine as a less invasive option for bone regeneration, turning what is often considered waste into a valuable resource.
Background: The search for effective antimicrobial agents to mitigate peri-implant infections remains a crucial aspect of implant dentistry. This study aimed to evaluate and compare the antimicrobial efficacy of i-PRF, A-PRF+, and enamel matrix derivative (EMD) on decontaminated rough and smooth titanium (Ti) discs.
Materials And Methods: Rough and smooth Ti discs were coated with multispecies biofilm and thoroughly debrided using a chitosan-bristled brush.