Publications by authors named "Shubham Laiwala"
Article Synopsis
- Prosthetic joint infections (PJIs) are a significant issue following orthopedic surgery, and bacteriophage therapy has potential as a treatment option, but more research is necessary on how these phages behave in the body.
- A study was conducted using a rat model to assess the pharmacokinetics of phage therapy by comparing different groups: controls without phage, PJIs without treatment, and PJIs treated with phages.
- Results indicated that phage concentrations in the tissues were similar across groups, with a short half-life of under 6 hours and maximum concentrations reached within 2 hours post-injection, setting the stage for future phage therapy studies in PJIs.
