Publications by authors named "Shubha Sankar Banerjee"
Adolescent-onset schizophrenia (AOS) is relatively rare, under-studied, and associated with more severe cognitive impairments and poorer outcomes than adult-onset schizophrenia. Neuroimaging has shown altered regional activations (first-order effects) and functional connectivity (second-order effects) in AOS compared to controls. The pairwise maximum entropy model (MEM) integrates first- and second-order factors into a single quantity called energy, which is inversely related to probability of occurrence of brain activity patterns.
View Article and Find Full Text PDFArticle Synopsis
- - Adolescent-onset schizophrenia (AOS) is a rare and poorly understood condition that leads to more severe cognitive impairments and worse outcomes compared to adult-onset schizophrenia.
- - Researchers used advanced neuroimaging techniques to study the brain activity of 23 individuals with AOS and 53 healthy controls during a cognitive task, finding that AOS patients performed significantly worse and exhibited higher energy patterns in their brain activities.
- - The study suggests that the combined evaluation of brain energy levels can provide insights into the cognitive deficits and associated psychopathology in AOS, highlighting the need for better understanding and potential treatment strategies.